Compile Data Set for Download or QSAR
maximum 50k data
Found 157 of ec50 for UniProtKB: Q76JU9
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563845(CHEMBL4793371)
Affinity DataEC50:  0.420nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563848(CHEMBL4782004)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563860(CHEMBL4788206)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563858(CHEMBL4785057)
Affinity DataEC50:  0.590nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563857(CHEMBL4797858)
Affinity DataEC50:  0.620nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563849(CHEMBL4797124)
Affinity DataEC50:  0.690nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563846(CHEMBL4787010)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563843(CHEMBL4798993)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563854(CHEMBL4791842)
Affinity DataEC50:  0.880nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204012(CHEMBL3955132)
Affinity DataEC50:  1nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563856(CHEMBL4800563)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563842(CHEMBL4798023)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563863(CHEMBL4787498)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563844(CHEMBL4781604)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362690(AMG-837 | CHEMBL1829173)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563859(CHEMBL4786335)
Affinity DataEC50:  2nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563862(CHEMBL4799453)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563847(CHEMBL4792075)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563855(CHEMBL4780641)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563851(CHEMBL4790921)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563853(CHEMBL4783033)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563840(CHEMBL4787628)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563850(CHEMBL4795763)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50386790(CHEMBL1829174 | CHEMBL2047159 | TAK-875)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563861(CHEMBL4784555)
Affinity DataEC50:  11nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50362690(AMG-837 | CHEMBL1829173)
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse GPR40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563852(CHEMBL4794233)
Affinity DataEC50:  18nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50343141(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
Affinity DataEC50:  19nMAssay Description:Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50405276(CHEMBL4167323)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mouse GPR40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50405440(CHEMBL4172828)
Affinity DataEC50:  31nMAssay Description:Agonist activity at mouse GPR40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563837(CHEMBL4783190)
Affinity DataEC50:  32nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM168191(US9688642, 2)
Affinity DataEC50:  38nMAssay Description:Agonist activity at mouse GPR40 assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50405293(CHEMBL4166892)
Affinity DataEC50:  42nMAssay Description:Agonist activity at mouse GPR40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344077(3-(4-((R)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344069(CHEMBL1777862 | rac-3-(4-(2-chloro-4-cyanophenoxy)...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267052(CHEMBL4082459)
Affinity DataEC50:  53nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244066(CHEMBL4083365)
Affinity DataEC50:  54nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563839(CHEMBL4792027)
Affinity DataEC50:  60nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344068(CHEMBL1777861 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  77nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344070(CHEMBL1777863 | rac-3-(4-(2-bromo-4-cyanophenoxy)p...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344071(CHEMBL1777864 | rac-3-(4-(4-cyanonaphthalen-1-ylox...)
Affinity DataEC50:  93nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344073(CHEMBL1777866 | rac-3-(4-(3-chloro-5-(trifluoromet...)
Affinity DataEC50:  95nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344078(CHEMBL1777872 | rac-3-(4-(2-p-tolyl-4,5,6,7-tetrah...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344080(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Affinity DataEC50:  104nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563838(CHEMBL4794904)
Affinity DataEC50:  110nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563841(CHEMBL4786299)
Affinity DataEC50:  120nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344079(CHEMBL1777873 | rac-3-(4-(cyclopentyloxy)phenyl)he...)
Affinity DataEC50:  124nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344067(CHEMBL1777860 | rac-3-(4-(2-methyl-4-(trifluoromet...)
Affinity DataEC50:  127nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344086(CHEMBL1777878 | cis-rac-5-(1-(4-(2-(difluoromethox...)
Affinity DataEC50:  136nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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