Affinity DataKi: 0.300nM EC50: 11nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.610nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Antagonist activity at NK-2 tachykinin receptors in rabbit pulmonary arteryMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Compound was evaluated for its competitive binding affinity towards human Prostanoid EP2 receptor in CHO cells expressing prostanoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.940nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.950nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.970nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 0.990nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -12.4kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nM ΔG°: -12.2kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to EP2 receptor (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -12.1kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 2nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Affinity DataKi: 2nM EC50: 11nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Affinity DataKi: 2nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -11.9kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 3nM EC50: 11nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nM ΔG°: -11.8kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity to EP2 receptor (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Binding affinity to EP2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nM ΔG°: -11.7kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nM ΔG°: -11.7kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMpH: 6.0Assay Description:Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nM ΔG°: -11.6kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity at human prostaglandin EP2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6nM EC50: 13nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair