Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50036368
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  310nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50:  2.70E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  8.00E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  9.00E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50:  9.70E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031090(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  1.27E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031093(2,3-Dichloro-4-(4-fluoro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031091(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  2.00E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  2.10E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031085(2,3-Dichloro-4-(4-fluoro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50:  2.50E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031083(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  3.45E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031088(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50:  3.55E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031083(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  3.60E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031079(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50:  4.00E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031092(5-Chloro-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-...)
Affinity DataIC50:  4.20E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031082(3-Bromo-2-chloro-4-(4-fluoro-phenyl)-5-(4-methanes...)
Affinity DataIC50:  4.40E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031089(2,3-Dibromo-4-(4-fluoro-phenyl)-5-(4-methanesulfon...)
Affinity DataIC50:  5.57E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031094(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  6.30E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031097(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  6.44E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031093(2,3-Dichloro-4-(4-fluoro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50:  6.90E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  7.20E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031082(3-Bromo-2-chloro-4-(4-fluoro-phenyl)-5-(4-methanes...)
Affinity DataIC50:  8.80E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031080(3-(4-Fluoro-phenyl)-5-iodo-2-(4-methanesulfonyl-ph...)
Affinity DataIC50:  9.23E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031095(3-(4-Fluoro-phenyl)-5-methanesulfonyl-2-(4-methane...)
Affinity DataIC50:  9.23E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031092(5-Chloro-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-...)
Affinity DataIC50:  9.40E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031096(3-(4-Fluoro-phenyl)-4,5-diiodo-2-(4-methanesulfony...)
Affinity DataIC50:  1.27E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031079(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50:  1.33E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.80E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)
Affinity DataIC50:  2.18E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50:  2.19E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50022309(3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-b...)
Affinity DataIC50:  2.84E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031081(2,2,2-Trifluoro-1-[4-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50:  2.98E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031095(3-(4-Fluoro-phenyl)-5-methanesulfonyl-2-(4-methane...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031086(1-[5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfony...)
Affinity DataIC50:  3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031084(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031086(1-[5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfony...)
Affinity DataIC50:  3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031084(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031096(3-(4-Fluoro-phenyl)-4,5-diiodo-2-(4-methanesulfony...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031091(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031080(3-(4-Fluoro-phenyl)-5-iodo-2-(4-methanesulfonyl-ph...)
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031090(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  3.73E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50022309(3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-b...)
Affinity DataIC50:  3.84E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031088(5-Bromo-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-p...)
Affinity DataIC50:  5.16E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031081(2,2,2-Trifluoro-1-[4-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50:  5.80E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031085(2,3-Dichloro-4-(4-fluoro-phenyl)-5-(4-methanesulfo...)
Affinity DataIC50:  6.50E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031089(2,3-Dibromo-4-(4-fluoro-phenyl)-5-(4-methanesulfon...)
Affinity DataIC50:  7.67E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  1.28E+6nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  1.80E+7nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank