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Found 32 Enz. Inhib. hit(s) with all data for entry = 50002762
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462606(CHEMBL4249022)
Affinity DataIC50:  2nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462612(CHEMBL4246480)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462622(CHEMBL4238198)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462613(CHEMBL4246864)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462611(CHEMBL4241473)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462620(CHEMBL4251272)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462605(CHEMBL4245244)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462619(CHEMBL4238378)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  7nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50398609(CHEMBL2141296 | IXAZOMIB CITRATE | Ixazomib | MLN2...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462604(CHEMBL4242666)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462625(CHEMBL4243375 | US11542283, Compound IV-8)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462610(CHEMBL4249503)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50:  11nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50:  13nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462618(CHEMBL4249917)
Affinity DataIC50:  13nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462614(CHEMBL4238931)
Affinity DataIC50:  20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462624(CHEMBL4248689)
Affinity DataIC50:  21nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462623(CHEMBL4246922)
Affinity DataIC50:  27nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462615(CHEMBL4243132)
Affinity DataIC50:  28nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462616(CHEMBL4249453)
Affinity DataIC50:  31nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462607(CHEMBL4239365)
Affinity DataIC50:  43nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462609(CHEMBL4250217)
Affinity DataIC50:  75nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  97nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462602(CHEMBL1813227)
Affinity DataIC50:  304nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462608(CHEMBL4244424)
Affinity DataIC50:  387nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462617(CHEMBL4245648)
Affinity DataIC50:  594nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Nanjing Forestry University

Curated by ChEMBL
LigandPNGBDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50:  7.95E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed