Found 70 Enz. Inhib. hit(s) with all data for entry = 50012030 
Affinity DataKi: 0.0780nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]SCH58261 from human adenosine 2A receptor expressed in HEK293 cell membranes incubated for 1.5 hrs by radioligand competition bin...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A1 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]CGS-21680 from human adenosine 2A receptor expressed in HEK293 cells incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Antagonist activity at human adenosine 2A receptor (409 to 412 residues) expressed in CHO cells using Ysi-poly-1-lysine as substrate incubated for 1 ...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2B receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A3 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]ZM241385 from human adenosine 2A receptor transfected in human HeLa cells incubated for 30 mins by competition radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine 2A receptor expressed in HEK293 cells incubated for 1.5 hrs by beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of human adenosine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A3 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Antagonist activity at human adenosine A2b receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 192nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells incubated for 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 255nMAssay Description:Inhibition of human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A1 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2B receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of human adenosine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 908nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A3 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Antagonist activity at human adenosine A2b receptor expressed in HEK293 cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Inhibition of human adenosine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.35E+3nMAssay Description:Inhibition of human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.72E+3nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A1 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of human adenosine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Displacement of [125I]-AB MECA from human adenosine A3 receptor expressed in CHO-K1 cells incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.83E+3nMAssay Description:Inhibition of human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.98E+3nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine 2B receptor expressed in HEK-293 cells incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in HeLa cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in HEK293T cells by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.05E+4nMAssay Description:Inhibition of human adenosine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.34E+4nMAssay Description:Antagonist activity at human adenosine 2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in CHO-K1 cells assessed as reduction in cAMP level in presence of 0.1 uM adenosine by f...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in cAMP production preincubated for 10 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at rat adenosine 2A receptor assessed as reduction in cAMP level in presence of 0.1 uM adenosineMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at adenosine 2A receptor (unknown origin) in presence of 1 uM adenosineMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in NECA-induced cAMP level incubated for 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in NECA-induced cAMP level incubated for 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Antagonist activity at human adenosine 2A receptor expressed in HEK293 cells assessed as reduction in NECA-induced cAMP level incubated for 15 mins b...More data for this Ligand-Target Pair
