TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: <180nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Mus musculus)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: <180nMAssay Description:To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 190nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Mus musculus)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 190nMAssay Description:To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 300nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 300nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: <300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 340nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 340nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 400nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 400nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 420nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 420nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 440nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 440nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 470nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 470nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 480nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 480nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 510nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 510nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 530nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 530nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 550nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
The Institute Of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 550nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair