Report error Found 3415 Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor'
Affinity DataKd: 1.30nM EC50: 27nMAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKd: 0.25nMAssay Description:The equilibrium binding constant to guinea pig cerebral cortex membranes was measuredMore data for this Ligand-Target Pair
Affinity DataKd: 8.10nMAssay Description:The equilibrium binding constant to pig cerebral cortex membranes was measuredMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 265nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:In vitro smooth muscle contraction activity in guinea pig stomach consisting of CCK/gastrin receptor subtypeMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Tested for the 50% inhibition level against [125I]- gastrin binding in AR42J cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Activity at human CCK2 receptor expressed in HEK293 cells assessed as level of [3H]inositol produced relative to controlMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.64nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 3.30nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 17nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.560nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.630nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 3.40nMAssay Description:Affinity against Cholecystokinin type B receptor expressed in CHO cells on rat brain.More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Displacement of [125I]CCK8-SO3 from human CCK2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 977nMAssay Description:Partial agonist activity at wild-type human CCK2R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Partial agonist activity at wild-type human CCK2R expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R T2.61N mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R V3.28T, S3.29T mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 282nMAssay Description:Agonist activity at human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Agonist activity at human CCK2R H7.39L mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R V6.51I, Y6.52F mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human CCK2R H7.39L mutant expressed in CHO cells assessed as intracellular calcium response by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 119nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 2.66nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 572nMAssay Description:Activity at CCK2R-MOPR coexpressed in CHO cells co-transfected with delta-6-Galphaqi4-myr assessed as intracellular calcium release by FLIPRMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.330nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.410nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Rat)
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at gastrin receptor in rat AR4-2J cells assessed as intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
