Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 6346
TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378001BDBM50378001(CHEMBL1627321 | US8748608, 36)
Affinity DataKi:  0.260nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378018BDBM50378018(CHEMBL1627322 | US8748608, 37)
Affinity DataKi:  0.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123847BDBM123847(US8748608, 21)
Affinity DataKi:  0.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219117BDBM50219117(US8748608, 9 | CHEMBL244562 | N-(4-(4-(2,3-dichlor...)
Affinity DataKi:  0.600nM IC50: 1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123854BDBM123854(US8748608, 47)
Affinity DataKi:  0.650nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123850BDBM123850(US8748608, 34 Enantiomer B | US8748608, 34 Enantio...)
Affinity DataKi:  0.900nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378006BDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi:  0.980nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123856BDBM123856(US8748608, 49)
Affinity DataKi:  1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123842BDBM123842(US8748608, 16)
Affinity DataKi:  3nM IC50: 1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123850BDBM123850(US8748608, 34 Enantiomer B | US8748608, 34 Enantio...)
Affinity DataKi:  1.10nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123840BDBM123840(US8748608, 12 | BDBM50219108)
Affinity DataKi:  1.10nM IC50: 1.20nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123849BDBM123849(US8748608, 23)
Affinity DataKi:  1.30nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123855BDBM123855(US8748608, 48)
Affinity DataKi:  1.30nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378014BDBM50378014(CHEMBL1627308 | US8748608, 35)
Affinity DataKi:  1.37nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219102BDBM50219102(US8748608, 10 | CHEMBL398175 | N-(4-(4-(2,3-dichlo...)
Affinity DataKi:  1.40nM IC50: 6.70nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219114BDBM50219114(US8748608, 11 | CHEMBL244773 | N-(4-(4-(2,3-dichlo...)
Affinity DataKi:  1.60nM IC50: 25.6nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123853BDBM123853(US8748608, 46)
Affinity DataKi:  1.60nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123843BDBM123843(US8748608, 17)
Affinity DataKi:  1.80nM IC50: 42nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123845BDBM123845(US8748608, 19)
Affinity DataKi:  1.80nM IC50: 3.90nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378003BDBM50378003(CHEMBL1627319 | US8748608, 44)
Affinity DataKi:  2.20nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123848BDBM123848(US8748608, 22)
Affinity DataKi:  2.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123844BDBM123844(US8748608, 18)
Affinity DataKi:  2.80nM IC50: 12.8nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219107BDBM50219107(CHEMBL394541 | US8748608, 14 | N-(4-(4-(2-methoxyp...)
Affinity DataKi:  2.90nM IC50: 42.6nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378004BDBM50378004(CHEMBL1627318 | US8748608, 45)
Affinity DataKi:  3.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378002BDBM50378002(CHEMBL1627320 | US8748608, 39)
Affinity DataKi:  4.60nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378005BDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi:  5.40nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123846BDBM123846(US8748608, 20)
Affinity DataKi:  11.7nM IC50: 5.40nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219113BDBM50219113(US8748608, 15 | CHEMBL244989 | N-(4-(4-(2-methoxyp...)
Affinity DataKi:  12nM IC50: 18.9nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123842BDBM123842(US8748608, 16)
Affinity DataIC50: 15.8nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123850BDBM123850(US8748608, 34 Enantiomer B | US8748608, 34 Enantio...)
Affinity DataKi:  16.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123840BDBM123840(US8748608, 12 | BDBM50219108)
Affinity DataIC50: 22.9nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219117BDBM50219117(US8748608, 9 | CHEMBL244562 | N-(4-(4-(2,3-dichlor...)
Affinity DataIC50: 41nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123841BDBM123841(US8748608, 13 | BDBM50219106)
Affinity DataKi:  49.2nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50378013BDBM50378013(CHEMBL1627309 | US8748608, 38)
Affinity DataKi:  62.1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 123847BDBM123847(US8748608, 21)
Affinity DataIC50: 88.3nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219107BDBM50219107(CHEMBL394541 | US8748608, 14 | N-(4-(4-(2-methoxyp...)
Affinity DataIC50: 175nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219113BDBM50219113(US8748608, 15 | CHEMBL244989 | N-(4-(4-(2-methoxyp...)
Affinity DataIC50: 179nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219114BDBM50219114(US8748608, 11 | CHEMBL244773 | N-(4-(4-(2,3-dichlo...)
Affinity DataIC50: 368nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
The United States of America As Represented By The Secretary of The Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50219102BDBM50219102(US8748608, 10 | CHEMBL398175 | N-(4-(4-(2,3-dichlo...)
Affinity DataIC50: 1.30E+3nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent