Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50008732
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076602BDBM50076602([9-(2-Bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076613BDBM50076613([9-(2-Bromo-4-isopropyl-phenyl)-8-methoxy-2-methyl...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076608BDBM50076608(7-(Butyl-ethyl-amino)-1,5-dimethyl-3-phenyl-1,3-di...)
Affinity DataKi:  3nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076609BDBM50076609(6-(Butyl-ethyl-amino)-2,7-dimethyl-9-(2,4,6-trimet...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076619BDBM50076619(9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amin...)
Affinity DataKi:  5nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076616BDBM50076616(9-(2-Bromo-4-isopropyl-phenyl)-6-(cyclopropylmethy...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076624BDBM50076624(6-(Cyclopropylmethyl-propyl-amino)-2,7-dimethyl-9-...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076615BDBM50076615(9-(2-Bromo-4-isopropyl-phenyl)-6-dipropylamino-2,7...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076623BDBM50076623(9-(2-Bromo-4-isopropyl-phenyl)-6-[cyclopropylmethy...)
Affinity DataKi:  12nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076620BDBM50076620(9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-pentylam...)
Affinity DataKi:  15nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076604BDBM50076604(6-(1-Ethyl-pentylamino)-2,7-dimethyl-9-(2,4,6-trim...)
Affinity DataKi:  17nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076614BDBM50076614(6-[Benzyl-(2-methoxy-ethyl)-amino]-9-(2-bromo-4-is...)
Affinity DataKi:  26nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076603BDBM50076603([9-(2-Bromo-4-isopropyl-phenyl)-8-cyclopropylmetho...)
Affinity DataKi:  31nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076607BDBM50076607(9-(2-Bromo-4-isopropyl-phenyl)-6-(1-methoxymethyl-...)
Affinity DataKi:  43nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076625BDBM50076625(9-(2-Bromo-4-isopropyl-phenyl)-6-[ethyl-(2-methoxy...)
Affinity DataKi:  48nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076618BDBM50076618(6-(Cyclopropylmethyl-propyl-amino)-2,7-dimethyl-9-...)
Affinity DataKi:  113nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076611BDBM50076611(9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amin...)
Affinity DataKi:  117nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076610BDBM50076610(6-(Butyl-ethyl-amino)-2,7-dimethyl-9-(2,4,6-trimet...)
Affinity DataKi:  124nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076606BDBM50076606(6-[Bis-(2-methoxy-ethyl)-amino]-9-(2-bromo-4-isopr...)
Affinity DataKi:  130nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076622BDBM50076622(6-Dipropylamino-2,7-dimethyl-9-(2,4,6-trimethyl-py...)
Affinity DataKi:  259nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076626BDBM50076626([9-(2-Bromo-4-isopropyl-phenyl)-2-methyl-8-morphol...)
Affinity DataKi:  345nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076617BDBM50076617(4-(Butyl-ethyl-amino)-3,6-dimethyl-1-phenyl-1,3-di...)
Affinity DataKi:  463nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076621BDBM50076621(6-[Bis-(2-methoxy-ethyl)-amino]-2,7-dimethyl-9-(2,...)
Affinity DataKi:  698nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076605BDBM50076605(9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amin...)
Affinity DataKi:  890nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076612BDBM50076612(9-(2-Bromo-4-isopropyl-phenyl)-6-(2-methoxy-ethyla...)
Affinity DataKi:  1.18E+3nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]TYR-oCRH as the displaced radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed