Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 2889
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

LigandPNGBDBM25869(2-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  8nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

LigandPNGBDBM25869(2-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  33nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

LigandPNGBDBM25871(1-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  50nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

LigandPNGBDBM25873(8-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]but...)
Affinity DataIC50:  75nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute

LigandPNGBDBM25872(2-{3-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]pro...)
Affinity DataIC50:  80nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

LigandPNGBDBM25874(2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-2,3-d...)
Affinity DataIC50:  95nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

LigandPNGBDBM25875(8-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}-8-aza...)
Affinity DataIC50:  112nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Medicines Institute

LigandPNGBDBM25876(4,4-dimethyl-1-{4-[4-(quinolin-2-yl)piperazin-1-yl...)
Affinity DataIC50:  146nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed