Compile Data Set for Download or QSAR
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Found 9 Enz. Inhib. hit(s) with all data for entry = 50013674
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13976(Aminobenzoic acid analog 5 | CHEMBL116605)
Affinity DataKi:  18nMAssay Description:Inhibitory constant of the compound was determined against Protein-tyrosine phosphatase 1B (PTB1B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13976(Aminobenzoic acid analog 5 | CHEMBL116605)
Affinity DataKi:  65nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133280(5-(3-(3-(3-hydroxy-2-(methoxycarbonyl)phenoxy)prop...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity of the compound was determined against protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133279(5-(3-Butyrylamino-phenyl)-isoxazole-3-carboxylic a...)
Affinity DataKi:  1.48E+5nMAssay Description:Binding affinity of the compound was determined against protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)
Affinity DataKi:  1.64E+5nMAssay Description:Inhibitory activity of the compound was determined against T cell protein tyrosine phosphatase (TCPTP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133280(5-(3-(3-(3-hydroxy-2-(methoxycarbonyl)phenoxy)prop...)
Affinity DataKi:  2.02E+5nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133279(5-(3-Butyrylamino-phenyl)-isoxazole-3-carboxylic a...)
Affinity DataKi:  6.34E+5nMAssay Description:Inhibitory constant of compound against T cell protein tyrosine phosphatase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant of the compound against Protein-tyrosine phosphatase 1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM48319(4-amino-2-hydroxy-benzoic acid | 4-amino-2-hydroxy...)
Affinity DataKd:  1.20E+3nMAssay Description:Dissociation constant of the compound against protein tyrosine phosphatase PTB1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed