Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50015236
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153255(2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  0.700nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4 alleleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.40nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153255(2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  1.80nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.90nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataKi:  2.70nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataKd:  4nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataEC50:  7.5nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153260(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(4...)
Affinity DataKi:  14nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataKi:  14.5nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153255(2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataEC50:  26.8nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  28.4nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  30.4nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153265(2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  39.1nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153265(2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  46nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153260(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(4...)
Affinity DataKi:  54.2nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153266(2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-N-m-tolyl-a...)
Affinity DataKi:  61.9nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  88.9nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153266(2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-N-m-tolyl-a...)
Affinity DataKi:  90.7nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153257(N-(4-Bromo-3-methyl-phenyl)-2-[4-(2-cyano-phenyl)-...)
Affinity DataEC50:  96nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  101nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153261(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(2...)
Affinity DataKi:  114nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153256(2-[4-(4-Benzhydryl-phenyl)-piperazin-1-yl]-N-m-tol...)
Affinity DataKi:  175nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153261(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(2...)
Affinity DataKi:  936nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153262(2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153261(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153258(2-(4-Biphenyl-4-yl-piperazin-1-yl)-N-m-tolyl-aceta...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153258(2-(4-Biphenyl-4-yl-piperazin-1-yl)-N-m-tolyl-aceta...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153256(2-[4-(4-Benzhydryl-phenyl)-piperazin-1-yl]-N-m-tol...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153267(2-[4-(4-Benzyl-phenyl)-piperazin-1-yl]-N-m-tolyl-a...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153267(2-[4-(4-Benzyl-phenyl)-piperazin-1-yl]-N-m-tolyl-a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153266(2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-N-m-tolyl-a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153260(2-[4-(4-Bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153265(2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153262(2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153262(2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed