Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 2165
LigandChemical structure of BindingDB Monomer ID 17689BDBM17689(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17703BDBM17703(N-(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]metho...)
Affinity DataKi:  0.5nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17704BDBM17704(N-(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]metho...)
Affinity DataKi:  0.5nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17705BDBM17705(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  0.5nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17687BDBM17687(N-(3-{[(2R)-1-methylpyrrolidin-2-yl]methoxy}-4-(tr...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17709BDBM17709(N-(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]metho...)
Affinity DataKi:  1.60nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17710BDBM17710(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17684BDBM17684(N-methyl-4-({2-[(3-{[(2R)-1-methylpyrrolidin-2-yl]...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17713BDBM17713(7-chloro-N-{4-chloro-3-[(4-methylpiperazin-1-yl)me...)
Affinity DataKi:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17688BDBM17688(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataKi:  2.80nM ΔG°:  -48.3kJ/mole IC50: 4.60nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17683BDBM17683(4-{[2-({3-[2-(dimethylamino)ethoxy]-4-(trifluorome...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17711BDBM17711(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataKi:  3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17701BDBM17701(4-[(2-{[4-chloro-3-(piperidin-4-ylmethoxy)phenyl]a...)
Affinity DataKi:  3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17691BDBM17691(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17702BDBM17702(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataKi:  3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17706BDBM17706(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  3.60nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17682BDBM17682(4-{[2-({4-chloro-3-[(4-methylpiperazin-1-yl)methyl...)
Affinity DataKi:  3.90nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17695BDBM17695(4-{[2-({4-chloro-3-[(4-methylpiperazin-1-yl)methyl...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17698BDBM17698(4-{[2-({4-chloro-3-[2-(dimethylamino)ethoxy]phenyl...)
Affinity DataKi:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17700BDBM17700(4-[(2-{[4-chloro-3-(morpholin-4-ylmethyl)phenyl]am...)
Affinity DataKi:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17699BDBM17699(4-{[2-({4-chloro-3-[2-(diethylamino)ethoxy]phenyl}...)
Affinity DataKi:  5nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17680BDBM17680(N-(4-chlorophenyl)-5-[(6,7-dimethoxyquinazolin-4-y...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17685BDBM17685(N-methyl-4-({2-[(3-{[(2R)-1-methylpyrrolidin-2-yl]...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17678BDBM17678(4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17712BDBM17712(4-{[7-chloro-2-({4-chloro-3-[(4-methylpiperazin-1-...)
Affinity DataKi:  10nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17694BDBM17694(4-{[2-({4-chloro-3-[(4-methylpiperazin-1-yl)methyl...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17696BDBM17696(4-({2-[(4-chlorophenyl)amino]-1,3-benzoxazol-5-yl}...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17690BDBM17690(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17708BDBM17708(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  20nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17707BDBM17707(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  25nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17692BDBM17692(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  40nM ΔG°:  -41.8kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17681BDBM17681(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-{1H-pyrro...)
Affinity DataKi:  48nM ΔG°:  -41.4kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17693BDBM17693(N-{4-chloro-3-[(4-methylpiperazin-1-yl)methyl]phen...)
Affinity DataKi:  128nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17679BDBM17679(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-(pyridin-...)
Affinity DataKi:  160nM ΔG°:  -38.4kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17686BDBM17686(N-methyl-4-{[2-({3-[2-(pyrrolidin-1-yl)ethoxy]-5-(...)
Affinity DataKi:  287nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 720nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 1.14E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 3.18E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 4.01E+3nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 4.37E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 4.00E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17697BDBM17697(4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...)
Affinity DataIC50: 4.00E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed