Compile Data Set for Download or QSAR
Report error Found 195 Enz. Inhib. hit(s) with all data for entry = 2710
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23698BDBM23698(4-chloro-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23700BDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23705BDBM23705(4-bromo-1-[(4-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 15nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23700BDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataIC50: 15nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23709BDBM23709(3-methyl-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1H-p...)
Affinity DataKi:  21nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23701BDBM23701(4-chloro-1-[(3-nitrophenyl)carbonyl]-1H-pyrazole |...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23702BDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23710BDBM23710(1-[(4-methylphenyl)carbonyl]-3-nitro-1H-pyrazole |...)
Affinity DataKi:  28nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23703BDBM23703(1-benzoyl-4-nitro-1H-pyrazole | N-Benzoylpyrazole ...)
Affinity DataKi:  34nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23704BDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataKi:  39nM ΔG°:  -42.3kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23698BDBM23698(4-chloro-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataIC50: 40nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23705BDBM23705(4-bromo-1-[(4-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23711BDBM23711(1-benzoyl-3-nitro-1H-pyrazole | N-Benzoylpyrazole ...)
Affinity DataKi:  46nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23709BDBM23709(3-methyl-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1H-p...)
Affinity DataIC50: 50nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23700BDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataIC50: 51nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23704BDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataIC50: 57nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23712BDBM23712(1-[(2-methylphenyl)carbonyl]-4-nitro-1H-pyrazole |...)
Affinity DataKi:  65nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23706BDBM23706(1-[(3,4-dichlorophenyl)carbonyl]-1H-pyrazole | N-B...)
Affinity DataKi:  104nM ΔG°:  -39.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23707BDBM23707(1-[(2-fluorophenyl)carbonyl]-5-methyl-3-nitro-1H-p...)
Affinity DataKi:  107nM ΔG°:  -39.8kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23726BDBM23726(2-methylbut-3-yn-2-yl 4-methoxybenzoate | 1,1-dime...)
Affinity DataKi:  110nM ΔG°:  -39.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23702BDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23700BDBM23700(methyl 1-[(4-chlorophenyl)carbonyl]-1H-pyrazole-5-...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23702BDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 120nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23706BDBM23706(1-[(3,4-dichlorophenyl)carbonyl]-1H-pyrazole | N-B...)
Affinity DataIC50: 125nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23701BDBM23701(4-chloro-1-[(3-nitrophenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 170nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23710BDBM23710(1-[(4-methylphenyl)carbonyl]-3-nitro-1H-pyrazole |...)
Affinity DataIC50: 190nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23713BDBM23713(4-chloro-1-[(2-methylphenyl)carbonyl]-1H-pyrazole ...)
Affinity DataKi:  230nM ΔG°:  -37.9kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23712BDBM23712(1-[(2-methylphenyl)carbonyl]-4-nitro-1H-pyrazole |...)
Affinity DataIC50: 240nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23714BDBM23714(4-bromo-1-[(3-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataKi:  250nM ΔG°:  -37.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23727BDBM23727(N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide | N,N-...)
Affinity DataKi:  290nM ΔG°:  -37.3kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23716BDBM23716(N-{4-[(3-methyl-1H-pyrazol-1-yl)carbonyl]phenyl}ac...)
Affinity DataKi:  300nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23715BDBM23715(4-bromo-1-[(2-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataKi:  300nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23701BDBM23701(4-chloro-1-[(3-nitrophenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 340nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23704BDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataIC50: 390nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23701BDBM23701(4-chloro-1-[(3-nitrophenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 680nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23728BDBM23728(N -[2-(2-methoxyphenoxy)acetyl]thiophene-2-carbohy...)
Affinity DataKi:  820nM ΔG°:  -34.7kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23717BDBM23717(4-chloro-1-[(2-chlorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.2kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23708BDBM23708(4-bromo-1-[(2,6-difluorophenyl)carbonyl]-1H-pyrazo...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23702BDBM23702(3-[(2,4-dimethylphenyl)carbonyl]-1-[(4-fluoropheny...)
Affinity DataIC50: 1.10E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23707BDBM23707(1-[(2-fluorophenyl)carbonyl]-5-methyl-3-nitro-1H-p...)
Affinity DataIC50: 1.20E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23712BDBM23712(1-[(2-methylphenyl)carbonyl]-4-nitro-1H-pyrazole |...)
Affinity DataIC50: 1.30E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23717BDBM23717(4-chloro-1-[(2-chlorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataIC50: 1.40E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23720BDBM23720(1-[(4-tert-butylphenyl)carbonyl]-4-chloro-1H-pyraz...)
Affinity DataIC50: 1.50E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23704BDBM23704(1-benzoyl-N-phenyl-1H-pyrazole-3-carboxamide | N-B...)
Affinity DataIC50: 1.50E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23707BDBM23707(1-[(2-fluorophenyl)carbonyl]-5-methyl-3-nitro-1H-p...)
Affinity DataIC50: 1.50E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23730BDBM23730(methyl 3-{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-...)
Affinity DataKi:  1.60E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23705BDBM23705(4-bromo-1-[(4-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 1.70E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23708BDBM23708(4-bromo-1-[(2,6-difluorophenyl)carbonyl]-1H-pyrazo...)
Affinity DataIC50: 1.80E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23715BDBM23715(4-bromo-1-[(2-methylphenyl)carbonyl]-1H-pyrazole |...)
Affinity DataIC50: 2.30E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Montana State University

LigandChemical structure of BindingDB Monomer ID 23698BDBM23698(4-chloro-1-[(4-fluorophenyl)carbonyl]-1H-pyrazole ...)
Affinity DataIC50: 2.50E+3nMAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
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