Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 3056
LigandChemical structure of BindingDB Monomer ID 27391BDBM27391(5,13,17-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50: 2nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27413BDBM27413(2-(2-aminopyrimidin-4-yl)-1-(2-fluoroethyl)-1H,4H,...)
Affinity DataIC50: 3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27390BDBM27390(2-(2-amino-5-bromopyrimidin-4-yl)-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 4nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27412BDBM27412(2-(2-aminopyrimidin-4-yl)-1-(cyclopropylmethyl)-1H...)
Affinity DataIC50: 4nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27406BDBM27406(2-(2-aminopyrimidin-4-yl)-1-(2,2,2-trifluoroethyl)...)
Affinity DataIC50: 5nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27351BDBM27351(2-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 7nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27421BDBM27421(2-[2-(phenylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 7nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27404BDBM27404(2-(2-aminopyrimidin-4-yl)-1-ethyl-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 8nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27382BDBM27382(2-(3-fluoropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...)
Affinity DataIC50: 9nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27344BDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 10nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27407BDBM27407(2-(2-aminopyrimidin-4-yl)-1-propyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 12nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27411BDBM27411(2-(2-aminopyrimidin-4-yl)-1-(2-methylpropyl)-1H,4H...)
Affinity DataIC50: 13nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27384BDBM27384(2-{1H-pyrrolo[2,3-b]pyridin-4-yl}-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 14nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27409BDBM27409(2-(2-aminopyrimidin-4-yl)-1-cyclobutyl-1H,4H,5H,6H...)
Affinity DataIC50: 14nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27383BDBM27383(2-(pyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]py...)
Affinity DataIC50: 20nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27410BDBM27410(2-(2-aminopyrimidin-4-yl)-1-butyl-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 23nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27397BDBM27397(2-(pyridin-4-yl)-1H,4H,5H,6H-pyrrolo[2,3-c]pyrrol-...)
Affinity DataIC50: 27nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27389BDBM27389(2-(2-aminopyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2...)
Affinity DataIC50: 28nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27408BDBM27408(2-(2-aminopyrimidin-4-yl)-1-(propan-2-yl)-1H,4H,5H...)
Affinity DataIC50: 42nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27393BDBM27393(3-methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 45nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27414BDBM27414(2-(2-aminopyrimidin-4-yl)-1-(4,4,4-trifluorobutyl)...)
Affinity DataIC50: 47nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27400BDBM27400(1-ethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...)
Affinity DataIC50: 67nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27403BDBM27403(2-(2-aminopyrimidin-4-yl)-1-methyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 88nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27418BDBM27418(2-(2-aminopyrimidin-4-yl)-1-(1-methylpiperidin-4-y...)
Affinity DataIC50: 120nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27405BDBM27405(2-(2-aminopyrimidin-4-yl)-1-(2-hydroxyethyl)-1H,4H...)
Affinity DataIC50: 138nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27388BDBM27388(JMC502647 Compound 7 | 2-(2-chloropyridin-4-yl)-1H...)
Affinity DataIC50: 147nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27398BDBM27398(2-(pyridin-4-yl)-1H,4H,5H,6H,7H,8H-pyrrolo[3,2-c]a...)
Affinity DataIC50: 158nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27402BDBM27402(2-(pyridin-4-yl)-1-(2,2,2-trifluoroethyl)-1H,4H,5H...)
Affinity DataIC50: 160nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27385BDBM27385(2-(9H-purin-6-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyr...)
Affinity DataIC50: 178nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27396BDBM27396(2-(pyridin-4-yl)-4H,5H,6H,7H-furo[3,2-c]pyridin-4-...)
Affinity DataIC50: 201nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27395BDBM27395(2-(pyridin-4-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazi...)
Affinity DataIC50: 210nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27422BDBM27422(2-[2-(benzylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 220nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27419BDBM27419(2-[2-(propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 259nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27426BDBM27426(N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2...)
Affinity DataIC50: 262nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27417BDBM27417(2-(2-aminopyrimidin-4-yl)-1-benzyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 290nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27424BDBM27424(N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2...)
Affinity DataIC50: 323nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27394BDBM27394(1-methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 404nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27420BDBM27420(2-{2-[(2-methylpropyl)amino]pyrimidin-4-yl}-1H,4H,...)
Affinity DataIC50: 636nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27423BDBM27423(2-{2-[(cyclohexylmethyl)amino]pyrimidin-4-yl}-1H,4...)
Affinity DataIC50: 655nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27399BDBM27399(4-oxo-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-...)
Affinity DataIC50: 863nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27425BDBM27425(2-methyl-N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]...)
Affinity DataIC50: 1.40E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27401BDBM27401(1-(2-hydroxyethyl)-2-(pyridin-4-yl)-1H,4H,5H,6H,7H...)
Affinity DataIC50: 3.30E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27415BDBM27415(2-(2-aminopyrimidin-4-yl)-1-cyclohexyl-1H,4H,5H,6H...)
Affinity DataIC50: 5.00E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27416BDBM27416(2-(2-aminopyrimidin-4-yl)-1-phenyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 5.00E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27386BDBM27386(2-phenyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-on...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27387BDBM27387(1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | pyrro...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27392BDBM27392(3-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 27381BDBM27381(2-(pyridin-3-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2009
Entry Details Article
PubMed