Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50039358
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(CHEMBL1651534 | N-Pyridazin-3-yl-4-(3-{[5-(trifluo...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of His-tagged human FAAH N-terminal transmembrane-deleted truncated form expressed in Escherichia coli preincubated for 60 mins before ole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(CHEMBL1651534 | N-Pyridazin-3-yl-4-(3-{[5-(trifluo...)
Affinity DataIC50:  7.40nMAssay Description:Irreversible inhibition of His-tagged rat FAAH N-terminal transmembrane-deleted truncated form expressed in Escherichia coli preincubated for 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(CHEMBL1651525 | N-Pyridin-3-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(CHEMBL1651525 | N-Pyridin-3-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335380(CHEMBL1651525 | N-Pyridin-3-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(CHEMBL1651534 | N-Pyridazin-3-yl-4-(3-{[5-(trifluo...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(CHEMBL1651533 | N-Pyrazin-2-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(CHEMBL1651533 | N-Pyrazin-2-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335378(CHEMBL1651533 | N-Pyrazin-2-yl-4-(3-{[5-(trifluoro...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(CHEMBL1651534 | N-Pyridazin-3-yl-4-(3-{[5-(trifluo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335377(CHEMBL1651534 | N-Pyridazin-3-yl-4-(3-{[5-(trifluo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed