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Found 10 Enz. Inhib. hit(s) with all data for entry = 50040025
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388101(CHEMBL2059380)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388100(CHEMBL2059379)
Affinity DataIC50:  4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388092(CHEMBL2059196)
Affinity DataIC50:  5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388097(CHEMBL2059375)
Affinity DataIC50:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388098(CHEMBL2059376)
Affinity DataIC50:  11nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388099(CHEMBL2059377)
Affinity DataIC50:  23nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388095(CHEMBL2059373)
Affinity DataIC50:  39nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388093(CHEMBL2059197)
Affinity DataIC50:  58nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388096(CHEMBL2059374)
Affinity DataIC50:  133nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388094(CHEMBL2059198)
Affinity DataIC50:  147nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed