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Found 26 Enz. Inhib. hit(s) with all data for entry = 50047205
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  12nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  25nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154284(CHEMBL3775664 | US10106508, Compound II-2)
Affinity DataIC50:  53nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154289(CHEMBL3774947)
Affinity DataIC50:  63nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  68nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154288(CHEMBL3774906)
Affinity DataIC50:  90nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154259(CHEMBL3775112)
Affinity DataIC50:  99nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154260(CHEMBL3775536)
Affinity DataIC50:  116nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154256(CHEMBL3775046)
Affinity DataIC50:  138nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50:  139nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154277(CHEMBL3774578 | US10106508, Compound II-3)
Affinity DataIC50:  163nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154287(CHEMBL3775459)
Affinity DataIC50:  187nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154257(CHEMBL3774396)
Affinity DataIC50:  211nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154290(CHEMBL3775285)
Affinity DataIC50:  245nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154284(CHEMBL3775664 | US10106508, Compound II-2)
Affinity DataIC50:  336nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154282(CHEMBL3775911)
Affinity DataIC50:  354nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154283(CHEMBL3774471)
Affinity DataIC50:  434nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154258(CHEMBL3775897)
Affinity DataIC50:  456nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154261(CHEMBL3774808)
Affinity DataIC50:  460nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154279(CHEMBL3775148)
Affinity DataIC50:  519nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154280(CHEMBL3774712)
Affinity DataIC50:  595nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154281(CHEMBL3774609)
Affinity DataIC50:  824nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154285(CHEMBL3774982)
Affinity DataIC50:  829nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50:  880nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154286(CHEMBL3774910 | US10106508, Compound II-4)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50154278(CHEMBL3775372 | US10106508, Compound II-5)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed