TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human wild type GST-tagged EGFR kinase domain expressed in insect Sf9 cells using pEY (4:1)/biotinylated pEY as substrate after 30 mins...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human wild type GST-tagged EGFR kinase domain expressed in insect Sf9 cells using pEY (4:1)/biotinylated pEY as substrate after 30 mins...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:Inhibition of gefitinib-resistant human GST-tagged EGFR L858R/T790M double mutant using pEY (4:1)/biotinylated pEY as substrate after 30 mins by ELIS...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:Inhibition of gefitinib-resistant human GST-tagged EGFR L858R/T790M double mutant using pEY (4:1)/biotinylated pEY as substrate after 30 mins by ELIS...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.80nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.80nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 420nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 420nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 950nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 950nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 6.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 6.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair