Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50047260
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253810BDBM50253810(R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253810BDBM50253810(R115866 | CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157605BDBM50157605(Liazal | R-75251 | Liarozole | US9963439, Liarozol...)
Affinity DataIC50: 18nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157727BDBM50157727(CHEMBL3786184)
Affinity DataIC50: 60nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157721BDBM50157721(CHEMBL3786620)
Affinity DataIC50: 110nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157717BDBM50157717(CHEMBL3786581)
Affinity DataIC50: 240nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157722BDBM50157722(CHEMBL3787323)
Affinity DataIC50: 270nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157611BDBM50157611(CHEMBL3787627)
Affinity DataIC50: 340nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31886BDBM31886(CHEMBL309282 | CD564)
Affinity DataIC50: 520nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157722BDBM50157722(CHEMBL3787323)
Affinity DataIC50: 680nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157724BDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50: 930nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157727BDBM50157727(CHEMBL3786184)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157721BDBM50157721(CHEMBL3786620)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033067BDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033067BDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157731BDBM50157731(CHEMBL3785511 | US9963439, Compound C)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157729BDBM50157729(CHEMBL3787691)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31886BDBM31886(CHEMBL309282 | CD564)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157604BDBM50157604(CHEMBL3786324)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157604BDBM50157604(CHEMBL3786324)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157605BDBM50157605(Liazal | R-75251 | Liarozole | US9963439, Liarozol...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157731BDBM50157731(CHEMBL3785511 | US9963439, Compound C)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157729BDBM50157729(CHEMBL3787691)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157724BDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157718BDBM50157718(CHEMBL3785701)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157608BDBM50157608(CHEMBL95949)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157719BDBM50157719(CHEMBL3785624)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157608BDBM50157608(CHEMBL95949)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157723BDBM50157723(CHEMBL3786927)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157728BDBM50157728(CHEMBL3785761)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157720BDBM50157720(CHEMBL3786340)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157728BDBM50157728(CHEMBL3785761)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157730BDBM50157730(CHEMBL3785557)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157719BDBM50157719(CHEMBL3785624)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157730BDBM50157730(CHEMBL3785557)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157723BDBM50157723(CHEMBL3786927)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157726BDBM50157726(CHEMBL3786043)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032675BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157720BDBM50157720(CHEMBL3786340)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157722BDBM50157722(CHEMBL3787323)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033077BDBM50033077(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157718BDBM50157718(CHEMBL3785701)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157717BDBM50157717(CHEMBL3786581)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157726BDBM50157726(CHEMBL3786043)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033077BDBM50033077(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032675BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157611BDBM50157611(CHEMBL3787627)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033066BDBM50033066(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033066BDBM50033066(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The University of Montana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157717BDBM50157717(CHEMBL3786581)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed