Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50001342
TargetCorticotropin-releasing factor receptor 1(Human)
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataEC50:  1.10nMAssay Description:Antagonist activity at human CRFR1 expressed in HEK293 cells assessed as inhibition of sauvagine-induced cAMP accumulation by measuring sauvagine EC5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50074501(Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...)
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276841(CHEMBL4161963)
Affinity DataIC50: 447nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276839(CHEMBL4170184)
Affinity DataIC50: 891nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed