Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50001716
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
TBA

Curated by ChEMBL
LigandPNGBDBM50383381(CHEMBL2070050 | CHEMBL2030554 | US9765037, Compoun...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Plasmodium falciparum CDPK4 using syntide-2 as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
TBA

Curated by ChEMBL
LigandPNGBDBM50389704(CHEMBL2070081 | US9518026, Example 9 | US9765037, ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum CDPK4 using syntide-2 as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM36336(CID24762166 | Purfalcamine, 1)
Affinity DataIC50: 13nMAssay Description:Inhibition of Plasmodium falciparum recombinant CDPK1 expressed in Escherichia coli expression system after 1 hr in presence of [gamma33P]ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM50321310(CHEMBL4175786 | US10688093, Compound 229_0226_0284...)
Affinity DataKi:  37nMAssay Description:Inhibition of Plasmodium falciparum recombinant CDPK1 expressed in Escherichia coli expression system after 1 hr in presence of [gamma33P]ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM50321309(CHEMBL4165173)
Affinity DataKi:  262nMAssay Description:Inhibition of Plasmodium falciparum recombinant CDPK1 expressed in Escherichia coli expression system after 1 hr in presence of [gamma33P]ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM50131992(5-Bromo-3-[2-(4-fluoro-phenyl)-2-oxo-ethylidene]-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Plasmodium falciparum 6His-tagged MRK expressed in Escherichia coli preincubated for 5 mins followed by [gamma32P]ATP addition by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
TBA

Curated by ChEMBL
LigandPNGBDBM50105767(3-[3-(2-Hydroxy-ethoxy)-phenyl]-1H-quinolin-2-one ...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Plasmodium falciparum MRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
TBA

Curated by ChEMBL
LigandPNGBDBM79181(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of Plasmodium falciparum His-tagged CDPK4 expressed in Escherichia coli BL21(DE3) using EGTA as substrate after 10 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed