Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50006785
TargetC-X-C chemokine receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50503347(CHEMBL4442431)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CXCR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50503347(CHEMBL4442431)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CXCR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50503346(CHEMBL4560254)
Affinity DataKi:  6.40nMAssay Description:Positive allosteric modulation of 5-HT2C receptor (unknown origin) assessed as increase in 5-HT-induced displacement of [3H]mesulergine by measuring ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM48076(ML173 | 3-azanyl-N-[[2,3-bis(fluoranyl)phenyl]meth...)
Affinity DataEC50:  95nMAssay Description:Positive allosteric modulation of human M4 AchRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50023229(CHEMBL3329755)
Affinity DataEC50:  190nMAssay Description:Positive allosteric modulation of M5 AchR (unknown origin) assessed as increase in acetylcholine-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503348(CHEMBL4238861)
Affinity DataEC50:  210nMAssay Description:Positive allosteric modulation of M1 AchR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50034774(CHEMBL3360927)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation of M1 AchR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM48044(VU0152099-1 | 3-amino-N-(1,3-benzodioxol-5-ylmethy...)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of rat M4 AchRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM277300(US10072005, Example 93)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulation of M1 AchR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM48076(ML173 | 3-azanyl-N-[[2,3-bis(fluoranyl)phenyl]meth...)
Affinity DataEC50:  2.40E+3nMAssay Description:Positive allosteric modulation of rat M4 AchRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed