Affinity DataIC50: 640nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease expressed using Benzoyl-Nle-Lys-Arg-Arg-AMC as substrate measured preincubated for 3 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged DENV3 NS5 RNA dependent RNA polymerase (272 to 900 residues) after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DENV3 2'-O-methyltransferase using m7G*pppA-RNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DENV2 2'-O-methyltransferase using m7G*pppA-RNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease expressed using Benzoyl-Nle-Lys-Arg-Arg-AMC as substrate measured preincubated for 3 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease using Boc-GRR-AMC as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged DENV2 NGC NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease expressed in human Huh7 cells after 3 days by Phospha-Light SEAP reporter gene AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of DENV4 NS2B-NS3 serine protease after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of DENV1 NS2B-NS3 serine protease after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of DENV3 NS2B-NS3 serine protease after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Affinity DataIC50: 4.82E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease using Bz-Nle-Lys-Arg-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease using Bz-Nle-Lys-Arg-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Inhibition of Dengue virus NS2B-NS3 serine protease expressed in mouse RAW 264.7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymerase expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.62E+3nMAssay Description:Inhibition of DENV4 NS2B-NS3 serine protease expressed in human Huh7 cells after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease expressed in human Huh7 cells after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataEC50: 5.84E+3nMAssay Description:Inhibition of DENV1 NS2B-NS3 serine protease expressed in human Huh7 cells after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair