Affinity DataIC50: 7nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activity by biomol green reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activity by biomol green reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human p97More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of p97 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activity by biomol green reagent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of p97 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of full length p97 (unknown origin) expressed in insect cells assessed as reduction in ATPase activity by NADH-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of VPS4B (unknown origin) by malachite green assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of VPS4B (unknown origin) assessed as reduction in ATPase activity in presence of activating fragment of substrate CHMP1BMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in p97-dependent UbG76V-GFP degradation incubated for 1 hr by luciferase reporter gene as...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of p97 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of p97 (unknown origin) by malachite green assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of p97 in HEK293 cells co-expressing GFP and hemagglutinin assessed as reduction in p97-dependent ERAD pathway by immunoblotting analysisMore data for this Ligand-Target Pair
TargetATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial(Homo sapiens)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ClpX (unknown origin) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before ATP addition and measured up to 120 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of p97 (unknown origin) assessed as reduction in ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before ATP addition and measured up to 120 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) pre-incubated for 10 mins before ATP addition and measured up to 120 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of p97 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-fused VCP (unknown origin) expressed in Escherichia coli BL21 star (DE3) pre-incubated for 60 mins before ATP addition and measured...More data for this Ligand-Target Pair
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to GST-tagged p97 (unknown origin) by CD spectroscopyMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to p97 (unknown origin) by SPR assayMore data for this Ligand-Target Pair