Compile Data Set for Download or QSAR
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Found 37 Enz. Inhib. hit(s) with all data for entry = 50010563
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012647(CHEMBL2396989)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  18nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012647(CHEMBL2396989)
Affinity DataIC50:  20nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  22nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  28nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540170(CHEMBL4636286)
Affinity DataIC50:  44nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540170(CHEMBL4636286)
Affinity DataIC50:  67nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50:  239nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50:  288nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540168(CHEMBL4644249)
Affinity DataIC50:  990nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540168(CHEMBL4644249)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50:  6.64E+3nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50:  7.33E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540166(CHEMBL4636311)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540166(CHEMBL4636311)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540170(CHEMBL4636286)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540165(CHEMBL4637913)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540164(CHEMBL4640948)
Affinity DataIC50:  7.36E+4nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540164(CHEMBL4640948)
Affinity DataIC50:  9.24E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540169(CHEMBL4648644)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540169(CHEMBL4648644)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540163(CHEMBL4637568)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540169(CHEMBL4648644)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540163(CHEMBL4637568)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540165(CHEMBL4637913)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540167(CHEMBL4642463)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540168(CHEMBL4644249)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540165(CHEMBL4637913)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540164(CHEMBL4640948)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540163(CHEMBL4637568)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012647(CHEMBL2396989)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540166(CHEMBL4636311)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed