Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50016868
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC1 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]-acetylated histones from human HDAC2 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50597917(CHEMBL5193563)
Affinity DataIC50: 41nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]-acetylated histones from HDAC1 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 540nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 610nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 740nMAssay Description:Displacement of [3H]-acetylated histones from HDAC3 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Mouse)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]-acetylated histones from mouse HDAC6 transfected in HEK-293T cells incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50087841(CHEMBL3426804)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50597917(CHEMBL5193563)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-acetylated histones HDAC6 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM36184(4-phenylbutanoate)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(butanoic acid | Butyrate | butanoic acid, 4)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(butanoic acid | Butyrate | butanoic acid, 4)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM26109(butanoic acid | Butyrate | butanoic acid, 4)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed