Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 455
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2714(3-[(2S)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 4.10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2700(3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]...)
Affinity DataIC50: 7.60nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2712(3-(1-methyl-1H-indol-3-yl)-4-{2-[(methylamino)meth...)
Affinity DataIC50: 9.80nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2715(3-[(2R)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2699(3-[2-(aminomethyl)-1H,2H,3H-benzo[b]pyrrolizin-9-y...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2702(3-[3-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2704(3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 16.5nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2703(3-[3-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2705(3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyr...)
Affinity DataIC50: 42nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2701(3-[2-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 47nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2713(3-[6,7,8,9-Tetrahydro-8-[(trimethylamino)methyl]py...)
Affinity DataIC50: 49nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 75nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2710(3-[8-Amino-7,8,9,10-tetrahydro-6H-azepino[1,2-a]in...)
Affinity DataIC50: 100nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2708(3-{2-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 110nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 121nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2709(3-{3-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 135nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2697(3-[6,7,8,9-Tetrahydropyrido[1,2-a]indol-10-yl]-4-(...)
Affinity DataIC50: 155nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2696(3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2707(3-[9-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 272nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2706(3-[7-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 400nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2698(3-{6H,7H,8H,9H,10H-azepino[1,2-a]indol-11-yl}-4-(1...)
Affinity DataIC50: 450nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2711(3-(1,2,3,4-Tetrahydropyrazino[1,2-a]indol-10-yl)-4...)
Affinity DataIC50: 540nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2715(3-[(2R)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 900nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2702(3-[3-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...)
Affinity DataIC50: 1.10E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2710(3-[8-Amino-7,8,9,10-tetrahydro-6H-azepino[1,2-a]in...)
Affinity DataIC50: 2.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2704(3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 2.60E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2700(3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]...)
Affinity DataIC50: 2.80E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2711(3-(1,2,3,4-Tetrahydropyrazino[1,2-a]indol-10-yl)-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2708(3-{2-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 3.30E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2699(3-[2-(aminomethyl)-1H,2H,3H-benzo[b]pyrrolizin-9-y...)
Affinity DataIC50: 3.90E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2709(3-{3-amino-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl}-4...)
Affinity DataIC50: 4.10E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2703(3-[3-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 4.50E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2712(3-(1-methyl-1H-indol-3-yl)-4-{2-[(methylamino)meth...)
Affinity DataIC50: 4.80E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataIC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2705(3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyr...)
Affinity DataIC50: 8.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2714(3-[(2S)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 1.21E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2706(3-[7-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 1.28E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2697(3-[6,7,8,9-Tetrahydropyrido[1,2-a]indol-10-yl]-4-(...)
Affinity DataIC50: 2.30E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2701(3-[2-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 2.40E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2707(3-[9-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 3.40E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2696(3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1...)
Affinity DataIC50: 6.80E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2713(3-[6,7,8,9-Tetrahydro-8-[(trimethylamino)methyl]py...)
Affinity DataIC50: 9.25E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2698(3-{6H,7H,8H,9H,10H-azepino[1,2-a]indol-11-yl}-4-(1...)
Affinity DataIC50: 1.00E+5nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed