Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 1838
LigandChemical structure of BindingDB Monomer ID 14457BDBM14457((+)-4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14461BDBM14461((+)-4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14459BDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14473BDBM14473(4-(2-{4-[(2S)-6,12-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14467BDBM14467(SCH 66336 analog | (+)-4-[2-[4-(8-Chloro-3,10-dibr...)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14469BDBM14469(4-(2-{4-[(2S)-6,12-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14477BDBM14477(4-(2-{4-[(2S)-6,12-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14463BDBM14463((+)-4-(3-Bromo-8,10-dichloro-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14471BDBM14471((-)-4-[2-[4-(3,7-Dibromo-8-chloro-6,11-dihydro-5H-...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14475BDBM14475(4-(2-{4-[(2S)-6-bromo-12,13-dichloro-4-azatricyclo...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14465BDBM14465((+)-4-(3-Bromo-8-chloro-10-fluoro-6,11-dihydro-5H-...)
Affinity DataIC50: 16.7nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14466BDBM14466(4-(2-{4-[(2S)-6-bromo-13-chloro-15-fluoro-4-azatri...)
Affinity DataIC50: 33.1nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14456BDBM14456(4-[2-(4-{6-bromo-13-chloro-4-azatricyclo[9.4.0.0^{...)
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14470BDBM14470((+)-4-(8-Chloro-3,7-dibromo-6,11-dihydro-5H-benzo-...)
Affinity DataIC50: 62nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14472BDBM14472((+)-4-[2-[4-(3,7-Dibromo-8-chloro-6,11-dihydro-5H-...)
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14476BDBM14476(4-[2-(4-{6-bromo-13-chloro-12-fluoro-4-azatricyclo...)
Affinity DataIC50: 86nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14458BDBM14458((-)-4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 88nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14455BDBM14455(4-[2-(4-{6-bromo-13-chloro-4-azatricyclo[9.4.0.0^{...)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14460BDBM14460(4-(2-{4-[(2S)-6,15-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 94nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14468BDBM14468(4-(2-{4-[(2S)-6,15-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 94nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14462BDBM14462((-)-4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 95nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14474BDBM14474(4-(2-{4-[(2R)-6,12-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14464BDBM14464((-)-4-(3-Bromo-8,10-dichloro-6,11-dihydro-5H-benzo...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14454BDBM14454(1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentad...)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14478BDBM14478(4-(2-{4-[(2R)-6,12-dibromo-13-chloro-4-azatricyclo...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:FPT activity was determined by measuring transfer of [3H] farnesyl from [3H]farnesyl pyrophosphate to the substrate His6-Ha-Ras-CVLS. The incorporate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed