Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 2196
TargetMajor prion protein(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357271(2-(((1s,4s)-4-((5- (cyanomethylthio)-3,4- diphenyl...)
Affinity DataIC50:  20nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMajor prion protein(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357270(2-(((1s,4s)-4-((5- (methylthio)-4-(5- methylthioph...)
Affinity DataIC50:  28nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMajor prion protein(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357273(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-3,4- diphe...)
Affinity DataIC50:  70nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMajor prion protein(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357274(2-(((1s,4s)-4-((4-(5- fluoropyridin-3-yl)-5- (meth...)
Affinity DataIC50:  220nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357271(2-(((1s,4s)-4-((5- (cyanomethylthio)-3,4- diphenyl...)
Affinity DataEC50:  11nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357270(2-(((1s,4s)-4-((5- (methylthio)-4-(5- methylthioph...)
Affinity DataEC50:  16nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357269(2-(((1s,4s)-4-((5- (ethylthio)-4-(2-fluoro-3- meth...)
Affinity DataEC50:  7nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357272(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-4-(3- meth...)
Affinity DataEC50:  2nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent