Compile Data Set for Download or QSAR
Report error Found 211 Enz. Inhib. hit(s) with all data for entry = 11289
LigandChemical structure of BindingDB Monomer ID 605286BDBM605286(US11667652, Example 81)
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605237BDBM605237(US11667652, Example 33)
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605397BDBM605397(US11667652, Example 191)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605307BDBM605307(US11667652, Example 102 | US11667652, Example 111)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605306BDBM605306(US11667652, Example 101)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605229BDBM605229(US11667652, Example 24)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605358BDBM605358(US11667652, Example 152)
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605315BDBM605315(US11667652, Example 109)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605321BDBM605321(US11667652, Example 115)
Affinity DataIC50: 0.0290nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605234BDBM605234(US11667652, Example 30)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605398BDBM605398(US11667652, Example 192)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605328BDBM605328(US11667652, Example 122)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605303BDBM605303(US11667652, Example 98 | US11667652, Example 99)
Affinity DataIC50: 0.0310nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605330BDBM605330(US11667652, Example 124)
Affinity DataIC50: 0.0330nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605268BDBM605268(US11667652, Example 63)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605303BDBM605303(US11667652, Example 98 | US11667652, Example 99)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605326BDBM605326(US11667652, Example 120)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605310BDBM605310(US11667652, Example 104)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605325BDBM605325(US11667652, Example 119)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605356BDBM605356(US11667652, Example 150)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605313BDBM605313(US11667652, Example 107)
Affinity DataIC50: 0.0360nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605349BDBM605349(US11667652, Example 143)
Affinity DataIC50: 0.0370nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605233BDBM605233(US11667652, Example 29)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605305BDBM605305(US11667652, Example 100)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605312BDBM605312(US11667652, Example 106)
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605271BDBM605271(US11667652, Example 66)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605417BDBM605417(US11667652, Example 211)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605415BDBM605415(US11667652, Example 209)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605241BDBM605241(US11667652, Example 37)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605402BDBM605402(US11667652, Example 196)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605393BDBM605393(US11667652, Example 187)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605391BDBM605391(US11667652, Example 185 | US11667652, Example 204)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605287BDBM605287(US11667652, Example 82)
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605223BDBM605223(US11667652, Example 18)
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605239BDBM605239(US11667652, Example 35)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605316BDBM605316(US11667652, Example 110)
Affinity DataIC50: 0.0450nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605302BDBM605302(US11667652, Example 97)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605278BDBM605278(US11667652, Example 73)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605327BDBM605327(US11667652, Example 121)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605281BDBM605281(US11667652, Example 76)
Affinity DataIC50: 0.0480nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605314BDBM605314(US11667652, Example 108)
Affinity DataIC50: 0.0480nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605375BDBM605375(US11667652, Example 169)
Affinity DataIC50: 0.0480nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605391BDBM605391(US11667652, Example 185 | US11667652, Example 204)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605401BDBM605401(US11667652, Example 195)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605384BDBM605384(US11667652, Example 178)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605416BDBM605416(US11667652, Example 210)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605404BDBM605404(US11667652, Example 198)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605406BDBM605406(US11667652, Example 200)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605331BDBM605331(US11667652, Example 125)
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605368BDBM605368(US11667652, Example 162)
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2023
Entry Details
US Patent

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