Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 6321
TargetCathepsin K(Human)
Medivir

US Patent
LigandPNGBDBM123101(US8735395, 5 | US11312693, Example 5)
Affinity DataKi:  0.600nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin K(Human)
Medivir

US Patent
LigandPNGBDBM123098(US8735395, 2 | US9200006, 2 | US10723709, Example ...)
Affinity DataKi:  1.10nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin K(Human)
Medivir

US Patent
LigandPNGBDBM123097(US8735395, 1 | US9200006, 1 | US10723709, Example ...)
Affinity DataKi:  1.60nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin K(Human)
Medivir

US Patent
LigandPNGBDBM123100(US8735395, 4 | US10723709, Example 4 | US11312693,...)
Affinity DataKi:  2.70nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin K(Human)
Medivir

US Patent
LigandPNGBDBM123099(US8735395, 3 | US10723709, Example 3 | US11312693,...)
Affinity DataKi:  4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetProcathepsin L(Human)
Medivir

US Patent
LigandPNGBDBM123100(US8735395, 4 | US10723709, Example 4 | US11312693,...)
Affinity DataKi:  300nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetProcathepsin L(Human)
Medivir

US Patent
LigandPNGBDBM123099(US8735395, 3 | US10723709, Example 3 | US11312693,...)
Affinity DataKi:  1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetProcathepsin L(Human)
Medivir

US Patent
LigandPNGBDBM123098(US8735395, 2 | US9200006, 2 | US10723709, Example ...)
Affinity DataKi:  1.70E+3nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetProcathepsin L(Human)
Medivir

US Patent
LigandPNGBDBM123097(US8735395, 1 | US9200006, 1 | US10723709, Example ...)
Affinity DataKi:  2.00E+3nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin S(Human)
Medivir

US Patent
LigandPNGBDBM123101(US8735395, 5 | US11312693, Example 5)
Affinity DataKi:  2.90E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin S(Human)
Medivir

US Patent
LigandPNGBDBM123100(US8735395, 4 | US10723709, Example 4 | US11312693,...)
Affinity DataKi:  1.45E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin S(Human)
Medivir

US Patent
LigandPNGBDBM123098(US8735395, 2 | US9200006, 2 | US10723709, Example ...)
Affinity DataKi:  2.10E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent

TargetCathepsin S(Human)
Medivir

US Patent
LigandPNGBDBM123097(US8735395, 1 | US9200006, 1 | US10723709, Example ...)
Affinity DataKi:  2.50E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent