Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 58
TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77064(US9695197, 4)
Affinity DataKi:  0.110nM ΔG°:  -56.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM50323697(thiamet-G | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(H...)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77047(US9695197, 3)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM70885(US9695197, 2)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM70719(US9695197, 1)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77064(US9695197, 4)
Affinity DataEC50:  3nMT: 2°CAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM50323697(thiamet-G | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(H...)
Affinity DataEC50:  13nMT: 2°CAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77863(US9695197, 5)
Affinity DataKi:  22nM ΔG°:  -43.7kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77047(US9695197, 3)
Affinity DataEC50:  29nMT: 2°CAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM70885(US9695197, 2)
Affinity DataEC50:  139nMT: 2°CAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM77863(US9695197, 5)
Affinity DataEC50:  349nMT: 2°CAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent