Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50586533
Substrate
n/a
Meas. Tech.
ChEMBL_2169000 (CHEMBL5054059)
IC50
410±n/a nM
Citation
 Hu, T; Zheng, G; Xue, D; Zhao, S; Li, F; Zhou, F; Zhao, F; Xie, L; Tian, C; Hua, T; Zhao, S; Xu, Y; Zhong, G; Liu, ZJ; Makriyannis, A; Stevens, RC; Tao, H Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools. J Med Chem 64:13752-13765 (2021) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50586533
Synonyms:
CHEMBL5090102
Type:
Small organic molecule
Emp. Form.:
C28H29N5O2
Mol. Mass.:
467.5622
SMILES:
Cc1c(nn(CCCCCO)c1-c1ccccc1)C(=O)Nc1cccc(c1)\N=N/c1ccccc1
Structure:
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