Affinity DataKi: 28nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Target4-aminobutyrate aminotransferase, mitochondrial(Rattus norvegicus)
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.43E+4nMAssay Description:Activity of GABA transaminase in rat brainMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of full-length human N-terminal FLAG-tagged PRMT5 expressed in Sf9 insect cells using histone H2A as peptide after 120 mins in presence of...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PI substrate incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of PRMT5 (unknown origin)/MEP50 (unknown origin) using histone H4 as substrate preincubated for 60 mins in presence of enzyme and SAMMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) using ULight4E-BP1 peptide as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues)/human N-terminal His-tagged MEP50 (2 to end residues) expressed in H...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
University Of Jinan
Curated by ChEMBL
University Of Jinan
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of full length recombinant human FLAG-tagged PRMT5/full length recombinant human His6-tagged MEP50 expressed in baculovirus infected Sf9 i...More data for this Ligand-Target Pair