Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 6S7H
Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.318nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.318nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.381nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of rat CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataIC50: 3nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)