Compile Data Set for Download or QSAR
Report error Found 30 of affinity data for UniProtKB/TrEMBL: O08663
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36590BDBM36590(FOS-72)
Affinity DataEC50:  0.0130nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36589BDBM36589(Ovalicin)
Affinity DataEC50:  0.0180nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36588BDBM36588(AGM-1470)
Affinity DataEC50:  0.0370nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36592BDBM36592(FOS-70)
Affinity DataEC50:  0.120nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36597BDBM36597(FOS-69)
Affinity DataEC50:  0.310nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36595BDBM36595(FOS-68)
Affinity DataEC50:  0.460nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36596BDBM36596(FOS-34)
Affinity DataEC50:  2.20nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36591BDBM36591(FOS-37)
Affinity DataEC50:  9.5nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468977BDBM468977(1-[2-[(3R,5S,6R)-5-Aamino- 6-(2,5- difluorophenyl)...)
Affinity DataIC50: 10.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468975BDBM468975(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 12.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468957BDBM468957(1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 21.9nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468978BDBM468978(1-[1-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 29.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468979BDBM468979(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 30.5nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468976BDBM468976((3S)-1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 32.1nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468958BDBM468958(1-[2-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 33.6nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468964BDBM468964(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 36.8nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 50547191BDBM50547191(CHEMBL4746468)
Affinity DataIC50: 40nMAssay Description:Inhibition of MetAP2 in mouse B cells assessed as reduction in IgG secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36598BDBM36598(FOS-67)
Affinity DataEC50:  40nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468972BDBM468972((3S)-1-[2-[(3R,5S,6R)-5-Amino-6-(2,5-difluoropheny...)
Affinity DataIC50: 48nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36599BDBM36599(FOS-201)
Affinity DataEC50:  56nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468980BDBM468980(1-[1-[(3R,5S,6R)-5-Amino- 6-(2,5- difluorophenyl)t...)
Affinity DataIC50: 60.3nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468961BDBM468961((3S)-1-[6-[4-[(3S,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 80.2nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468974BDBM468974(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 94.7nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468959BDBM468959(1-[2-[4-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)...)
Affinity DataIC50: 103nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36593BDBM36593(FOS-64)
Affinity DataEC50:  110nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468960BDBM468960(1-[2-[4-[(3R,5S,6R)-5- Amino-6-(2,5- difluoropheny...)
Affinity DataIC50: 111nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468963BDBM468963(1-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluorophenyl)tet...)
Affinity DataIC50: 123nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468973BDBM468973(1-[2-[(3R,5S,6R)-5-Amino-6- (2,5- difluorophenyl)t...)
Affinity DataIC50: 154nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 468981BDBM468981((3S)-1-[2-[1-[(3R,5S,6R)-5-Amino-6-(2,5-difluoroph...)
Affinity DataIC50: 283nMAssay Description:The compounds exemplified herein are tested essentially as described below and exhibit an IC50 for the human and mouse MetAP2 assay as shown in Table...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetMethionine aminopeptidase 2(Mouse)
Massachusetts Institute of Technology

LigandChemical structure of BindingDB Monomer ID 36594BDBM36594(FOS-202)
Affinity DataEC50:  2.80E+3nMpH: 7.5Assay Description:Proliferation assay using bovine aortic endothelial cell (BAEC) line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed