Compile Data Set for Download or QSAR
Report error Found 30 of affinity data for UniProtKB/TrEMBL: P09391
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646536BDBM50646536(CHEMBL5593490)
Affinity DataKi:  0.700nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646534BDBM50646534(CHEMBL5590961)
Affinity DataKi:  1.30nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646536BDBM50646536(CHEMBL5593490)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646537BDBM50646537(CHEMBL5594525)
Affinity DataIC50: 2nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646538BDBM50646538(CHEMBL5593011)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646534BDBM50646534(CHEMBL5590961)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646541BDBM50646541(CHEMBL5593588)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646539BDBM50646539(CHEMBL5595990)
Affinity DataIC50: 15nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataIC50: 44nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646533BDBM50646533(CHEMBL5593651)
Affinity DataIC50: 56nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646534BDBM50646534(CHEMBL5590961)
Affinity DataEC50:  123nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646536BDBM50646536(CHEMBL5593490)
Affinity DataEC50:  131nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataIC50: 132nMAssay Description:Inhibition of C-terminal His-tagged full length Escherichia coli GIpG expressed in Escherichia coli C43 (DE3) using Ac-RVRHA-4mc as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataEC50:  173nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616103BDBM50616103(CHEMBL5419931)
Affinity DataIC50: 300nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646540BDBM50646540(CHEMBL5590380)
Affinity DataIC50: 330nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646538BDBM50646538(CHEMBL5593011)
Affinity DataEC50:  337nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646537BDBM50646537(CHEMBL5594525)
Affinity DataEC50:  424nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616102BDBM50616102(CHEMBL5405012)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646533BDBM50646533(CHEMBL5593651)
Affinity DataEC50:  1.61E+3nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572958BDBM50572958(CHEMBL4856971)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50199883BDBM50199883(cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...)
Affinity DataIC50: 1.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2016
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572956BDBM50572956(CHEMBL4855230)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 165197BDBM165197((4S)‐3‐butyl‐4‐(pent‐...)
Affinity DataIC50: 4.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2016
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572960BDBM50572960(CHEMBL4859980)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572957BDBM50572957(CHEMBL4871112)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572959BDBM50572959(CHEMBL4854450)
Affinity DataIC50: 3.10E+5nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572955BDBM50572955(CHEMBL4861272)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed