TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataKi: 0.0160nMAssay Description:Binding affinity to Src (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.150nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant GST-tagged c-Src catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-l...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataKd: 0.210nMAssay Description:Binding constant for SRC kinase domainMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataKd: 0.210nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataKd: 0.210nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataKd: 0.210nMAssay Description:Binding constant for SRC kinase domainMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.220nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Binding affinity for Src SH2 domain in scintillation proximity binding assay (SPA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibitory concentration against SH2 domain of human p60 Src tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.310nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.330nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.400nMT: 2°CAssay Description:Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human SRC by time-resolved fluorescence or time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of 6x-His-tagged human Src kinase domain (T250 to L536 residues) expressed in Sf9 cells incubated for 2 hrs in presence of biotinylated cd...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.480nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hunan University of Science and Technology
Curated by ChEMBL
Hunan University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Src (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair

3D Structure (crystal)






























