Compile Data Set for Download or QSAR
Report error Found 152 of affinity data for UniProtKB/TrEMBL: P66004
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119876BDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  37nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 31044BDBM31044(1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1...)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 43224BDBM43224(SMR000278513 | MLS000717146 | 1-ethyl-6-methyl-3-[...)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50392849BDBM50392849(CHEMBL2151190 | US9073941, 612)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50438910BDBM50438910(CHEMBL1450796 | US9073941, 618)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 34905BDBM34905(1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazi...)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188292BDBM188292(US9073941, 620)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50438912BDBM50438912(CHEMBL1096283 | US9073941, 619 | Walrycin B | MAT-...)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188289BDBM188289(US9073941, 614)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188288BDBM188288(US9073941, 613)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188291BDBM188291(US9073941, 616)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188290BDBM188290(US9073941, 615)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188293BDBM188293(US9073941, 621)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 36527BDBM36527(1,6-dimethyl-3-phenyl-1H,5H,6H,7H-pyrimido[5,4-e][...)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188304BDBM188304(US9073941, 905)
Affinity DataIC50: 40nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50420474BDBM50420474(CHEMBL2086889 | US9073941, 607)
Affinity DataIC50: 60nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188286BDBM188286(US9073941, 605)
Affinity DataIC50: 70nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 34671BDBM34671(1,3,6-Trimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-...)
Affinity DataIC50: 80nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119877BDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119881BDBM119881(K906-3584)
Affinity DataIC50: 100nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 40314BDBM40314(3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...)
Affinity DataIC50: 100nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 54927BDBM54927(SMR000282064 | 4-[(phenylmethyl)amino]naphthalene-...)
Affinity DataIC50: 100nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188285BDBM188285(US9073941, 604)
Affinity DataIC50: 140nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119878BDBM119878(SL827 | US9073941, 500)
Affinity DataKi:  140nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119880BDBM119880(SL418)
Affinity DataKi:  143nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188287BDBM188287(US9073941, 608)
Affinity DataIC50: 190nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 31040BDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 230nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 119879BDBM119879(SL917 | US9073941, 505)
Affinity DataKi:  233nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 32062BDBM32062(SMR000060333 | MLS000054842 | N-(1-butyl-3-cyanopy...)
Affinity DataIC50: 520nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 22858BDBM22858(2-nitro-9,10-dihydrophenanthrene-9,10-dione | NSC2...)
Affinity DataIC50: 640nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 92887BDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50: 650nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50099737BDBM50099737(CHEMBL417727 | cid_254021 | 2-Amino-phenanthrene-9...)
Affinity DataIC50: 670nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 119876BDBM119876(SL932 | US9073941, 503)
Affinity DataIC50: 700nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 119879BDBM119879(SL917 | US9073941, 505)
Affinity DataIC50: 840nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 119877BDBM119877(SL809 | US9073941, 502)
Affinity DataIC50: 840nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188309BDBM188309(US9073941, 1006)
Affinity DataIC50: 860nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188303BDBM188303(US9073941, 903)
Affinity DataIC50: 860nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 34697BDBM34697(cid_4101144 | SMR000154973 | N-(1-butan-2-yl-3-cya...)
Affinity DataIC50: 870nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188308BDBM188308(US9073941, 1005)
Affinity DataIC50: 900nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 92887BDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50: 900nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50438918BDBM50438918(DNDI1417416 | CHEMBL2094689 | US9073941, 606)
Affinity DataIC50: 960nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 119878BDBM119878(SL827 | US9073941, 500)
Affinity DataIC50: 960nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188307BDBM188307(US9073941, 1002)
Affinity DataIC50: 980nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188311BDBM188311(US9073941, 1008)
Affinity DataIC50: 1.05E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188306BDBM188306(US9073941, 1001)
Affinity DataIC50: 1.08E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 76505BDBM76505(SMR000241658 | ethyl 1-(3-methoxypropyl)-2-(phenyl...)
Affinity DataIC50: 1.31E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188310BDBM188310(US9073941, 1007)
Affinity DataIC50: 1.36E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Weill Cornell Medical College

LigandChemical structure of BindingDB Monomer ID 92887BDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50: 1.50E+3nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188241BDBM188241(US9073941, 523)
Affinity DataIC50: 1.60E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 188298BDBM188298(US9073941, 803)
Affinity DataIC50: 1.62E+3nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
US Patent

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