Compile Data Set for Download or QSAR
Report error Found 656 of affinity data for UniProtKB/TrEMBL: Q9UIQ6
TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271230BDBM271230(US10059720, Example 45 | US10975091, Example 45)
Affinity DataIC50: 0.890nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271230BDBM271230(US10059720, Example 45 | US10975091, Example 45)
Affinity DataIC50: 0.890nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271257BDBM271257(US10059720, Example 72 | US10975091, Example 72)
Affinity DataIC50: 0.940nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271257BDBM271257(US10059720, Example 72 | US10975091, Example 72)
Affinity DataIC50: 0.940nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271275BDBM271275(US10059720, Example 90 | US10975091, Example 90)
Affinity DataIC50: 0.950nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271275BDBM271275(US10059720, Example 90 | US10975091, Example 90)
Affinity DataIC50: 0.950nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271198BDBM271198(US10059720, Example 13 | US10975091, Example 13)
Affinity DataIC50: 1nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271198BDBM271198(US10059720, Example 13 | US10975091, Example 13)
Affinity DataIC50: 1nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271277BDBM271277(US10059720, Example 92 | US10975091, Example 92)
Affinity DataIC50: 1.20nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271277BDBM271277(US10059720, Example 92 | US10975091, Example 92)
Affinity DataIC50: 1.20nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271272BDBM271272(US10059720, Example 87 | US10975091, Example 87)
Affinity DataIC50: 1.30nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271330BDBM271330(US10059720, Example 145 | US10975091, Example 145)
Affinity DataIC50: 1.30nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271190BDBM271190(US10059720, Example 6 | US10975091, Example 6)
Affinity DataIC50: 1.30nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271330BDBM271330(US10059720, Example 145 | US10975091, Example 145)
Affinity DataIC50: 1.30nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271272BDBM271272(US10059720, Example 87 | US10975091, Example 87)
Affinity DataIC50: 1.30nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271190BDBM271190(US10059720, Example 6 | US10975091, Example 6)
Affinity DataIC50: 1.30nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271288BDBM271288(US10059720, Example 103 | US10975091, Example 103)
Affinity DataIC50: 1.40nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271288BDBM271288(US10059720, Example 103 | US10975091, Example 103)
Affinity DataIC50: 1.40nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271280BDBM271280(US10059720, Example 95 | US10975091, Example 95)
Affinity DataIC50: 1.5nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271218BDBM271218(US10059720, Example 33 | US10975091, Example 33)
Affinity DataIC50: 1.5nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271218BDBM271218(US10059720, Example 33 | US10975091, Example 33)
Affinity DataIC50: 1.5nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271232BDBM271232(US10059720, Example 47 | US10975091, Example 47)
Affinity DataIC50: 1.5nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271232BDBM271232(US10059720, Example 47 | US10975091, Example 47)
Affinity DataIC50: 1.5nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271280BDBM271280(US10059720, Example 95 | US10975091, Example 95)
Affinity DataIC50: 1.5nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271245BDBM271245(US10059720, Example 60 | US10975091, Example 60)
Affinity DataIC50: 1.60nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271245BDBM271245(US10059720, Example 60 | US10975091, Example 60)
Affinity DataIC50: 1.60nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271233BDBM271233(US10059720, Example 48 | US10975091, Example 48)
Affinity DataIC50: 1.60nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271258BDBM271258(US10059720, Example 73 | US10975091, Example 73)
Affinity DataIC50: 1.60nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271233BDBM271233(US10059720, Example 48 | US10975091, Example 48)
Affinity DataIC50: 1.60nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271258BDBM271258(US10059720, Example 73 | US10975091, Example 73)
Affinity DataIC50: 1.60nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 401355BDBM401355(US10005762, Example 35)
Affinity DataIC50: 1.60nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50614477BDBM50614477(CHEMBL5267589)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to insulin regulated aminopeptidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271229BDBM271229(US10059720, Example 44 | US10975091, Example 44)
Affinity DataIC50: 1.80nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271246BDBM271246(US10059720, Example 61 | US10975091, Example 61)
Affinity DataIC50: 1.80nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 401368BDBM401368(US10005762, Example 48)
Affinity DataIC50: 1.80nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271229BDBM271229(US10059720, Example 44 | US10975091, Example 44)
Affinity DataIC50: 1.80nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271246BDBM271246(US10059720, Example 61 | US10975091, Example 61)
Affinity DataIC50: 1.80nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271252BDBM271252(US10059720, Example 67 | US10975091, Example 67)
Affinity DataIC50: 1.80nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271210BDBM271210(US10059720, Example 25 | US10975091, Example 25)
Affinity DataIC50: 1.80nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50346448BDBM50346448(2-(2-(((2S,6S,13S,E)-13-Amino-2-(4-hydroxybenzyl)-...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of catalytic activity of recombinant human IRAP transfected in human HEK-293 cells assessed as cleavage of substrate L-leucine-p-nitroanil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271252BDBM271252(US10059720, Example 67 | US10975091, Example 67)
Affinity DataIC50: 1.80nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271210BDBM271210(US10059720, Example 25 | US10975091, Example 25)
Affinity DataIC50: 1.80nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271211BDBM271211(US10059720, Example 26 | US10975091, Example 26)
Affinity DataIC50: 1.90nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271211BDBM271211(US10059720, Example 26 | US10975091, Example 26)
Affinity DataIC50: 1.90nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271290BDBM271290(US10059720, Example 105 | US10975091, Example 105)
Affinity DataIC50: 1.90nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271290BDBM271290(US10059720, Example 105 | US10975091, Example 105)
Affinity DataIC50: 1.90nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 50245396BDBM50245396(CHEMBL4101200)
Affinity DataIC50: 2nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271241BDBM271241(US10059720, Example 56 | US10975091, Example 56)
Affinity DataIC50: 2nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 271241BDBM271241(US10059720, Example 56 | US10975091, Example 56)
Affinity DataIC50: 2nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 401389BDBM401389(US10005762, Example 69)
Affinity DataIC50: 2.10nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

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