Compile Data Set for Download or QSAR
Report error Found 18 of affinity data for UniProtKB/TrEMBL: Q9Z2J6
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356677BDBM50356677(CHEMBL1917592)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344991BDBM50344991(2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50: 1nMAssay Description:Binding affinity to mouse CRTh2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356669BDBM50356669(CHEMBL1917584)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200271BDBM50200271(4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312906BDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006830BDBM50006830(CHEMBL3236948)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21610BDBM21610(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  5nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401097BDBM50401097(CHEMBL2204469)
Affinity DataIC50: 7nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442299BDBM50442299(CHEMBL2442750)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-prostaglandin D2 from mouse CRTh2 receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21603BDBM21603(2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-d...)
Affinity DataKi:  22nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296848BDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]PGD2 from mouse CRTh2 receptor expressed in K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21605BDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  33nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356646BDBM50356646(CHEMBL1917389)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21611BDBM21611(2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  88nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442299BDBM50442299(CHEMBL2442750)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at mouse CRTh2 receptor expressed in CHO-K1 cells assessed as inhibition of [125S]-GTP-gamma-S binding after 50 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21543BDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296848BDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)
Affinity DataIC50: 167nMAssay Description:Antagonist activity against mouse CRTh2 receptor expressed in K562 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Mouse)
Merck Serono

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21597BDBM21597(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  480nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed