Compile Data Set for Download or QSAR
Report error Found 2078 of affinity data for UniProtKB/TrEMBL: P00338
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 489093BDBM489093(US10961200, Compound 473 | 2-(5- (cyclopropylmethy...)
Affinity DataKd:  0.00100nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 489092BDBM489092(US10961200, Compound 471 | 2-(3-(3- cydopropoxy-4-...)
Affinity DataKd:  0.00400nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 537077BDBM537077(US11247971, Cmpd ID 400)
Affinity DataKd:  0.00800nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 537017BDBM537017(US11247971, Cmpd ID 340)
Affinity DataKd:  0.0160nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546973BDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)
Affinity DataKd:  0.0193nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547002BDBM50547002(CHEMBL4753379 | US11247971, Cmpd ID 449 | US117521...)
Affinity DataKd:  0.0634nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546993BDBM50546993(CHEMBL4748782 | US11247971, Cmpd ID 408 | US117521...)
Affinity DataKd:  0.0667nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572932BDBM50572932(CHEMBL4850573)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572931BDBM50572931(CHEMBL4855986)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250656BDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)
Affinity DataKd:  0.110nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250656BDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)
Affinity DataKd:  0.110nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546988BDBM50546988(CHEMBL4787852 | US11247971, Cmpd ID 411)
Affinity DataKd:  0.123nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572933BDBM50572933(CHEMBL4861379)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572934BDBM50572934(CHEMBL4847068)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250677BDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)
Affinity DataKd:  0.330nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572930BDBM50572930(CHEMBL4873879)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50569438BDBM50569438(CHEMBL4847591)
Affinity DataKd:  0.440nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572929BDBM50572929(CHEMBL4864519)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597908BDBM50597908(CHEMBL5181496)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597908BDBM50597908(CHEMBL5181496)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 489147BDBM489147(US10961200, Compound 528 | 2-(5- (cyclopropylmethy...)
Affinity DataKd:  0.910nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753567BDBM753567(US20250205203, Example 2)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753567BDBM753567(US20250205203, Example 2)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546971BDBM50546971(CHEMBL4777867 | US11247971, Cmpd ID 262 | US202502...)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753513BDBM753513(US20250205203, Example 1)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753594BDBM753594(US20250205203, Example 9)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546980BDBM50546980(CHEMBL4792513)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753593BDBM753593(US20250205203, Example 8)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753592BDBM753592(US20250205203, Example 7)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753591BDBM753591(US20250205203, Example 6)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753590BDBM753590(US20250205203, Example 5)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753589BDBM753589(US20250205203, Example 4)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 753570BDBM753570(US20250205203, Example 3)
Affinity DataIC50: 1nMAssay Description:Compounds were dissolved in DMSO and preincubated with human recombinant C-terminal His-tagged LDHA (0.070 μg/mL) for 10 min at room temperature in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 489129BDBM489129(US10961200, Compound 510 | 2-(5- (cyclopropylmethy...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 489104BDBM489104(US10961200, Compound 485 | 2-(5- (cyclopropylmethy...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to LDHA (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597906BDBM50597906(CHEMBL5183539)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103568BDBM50103568(CHEMBL3335794)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human His-tagged LDHA in absence of NADH by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597916BDBM50597916(CHEMBL5201115)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597916BDBM50597916(CHEMBL5201115)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597896BDBM50597896(CHEMBL5181996)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597896BDBM50597896(CHEMBL5181996)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597915BDBM50597915(CHEMBL5185237)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597913BDBM50597913(CHEMBL5194549)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597913BDBM50597913(CHEMBL5194549)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597915BDBM50597915(CHEMBL5185237)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103568BDBM50103568(CHEMBL3335794)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616100BDBM50616100(CHEMBL5416627)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human LDHAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103568BDBM50103568(CHEMBL3335794)
Affinity DataIC50: 2.60nMAssay Description:Competitive inhibition of human LDH5 in presence of NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103568BDBM50103568(CHEMBL3335794)
Affinity DataIC50: 2.60nMAssay Description:Competitive inhibition of recombinant human LDHA in the presence of NADH by resazurin dye reduction methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597909BDBM50597909(CHEMBL5196929)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
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