Compile Data Set for Download or QSAR
Report error Found 7704 of affinity data for UniProtKB/TrEMBL: P21453
TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195889(US9670220, 33)
Affinity DataEC50:  100nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195890(US9670220, 35)
Affinity DataEC50:  250nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195892(US9670220, 47)
Affinity DataEC50: >3.20E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195893(US9670220, 53)
Affinity DataEC50: >3.20E+4nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195894(US9670220, 57)
Affinity DataEC50: >3.20E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195895(US9670220, 73)
Affinity DataEC50:  10nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195896(US9670220, 76)
Affinity DataEC50:  250nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195897(US9670220, 77)
Affinity DataEC50:  32nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM195899(US9670220, 85)
Affinity DataEC50: >3.20E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196174(US9670220, 89)
Affinity DataEC50:  1.30E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196179(US9670220, 146)
Affinity DataEC50: >3.20E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196180(US9670220, 156)
Affinity DataEC50:  630nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196198(US9670220, 157)
Affinity DataEC50:  630nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196211(US9670220, 175)
Affinity DataEC50: >3.20E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196221(US9670220, 211)
Affinity DataEC50:  790nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196260(US9670220, 227)
Affinity DataEC50:  1.00E+3nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196261(US9670220, 271)
Affinity DataEC50:  630nMT: 2°CAssay Description:The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196263(US9670220, 277)
Affinity DataEC50:  6.30E+3nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196265(US9670220, 278 | US9670220, 307)
Affinity DataEC50: >1.00E+4nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196267(US9670220, 283)
Affinity DataEC50: >3.20E+4nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196286(US9670220, 306)
Affinity DataEC50: >1.00E+4nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM196265(US9670220, 278 | US9670220, 307)
Affinity DataEC50: >1.00E+4nMAssay Description:The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255775(N-(1H-Tetrazol-5-yl)methyl-4-octylbenzylamine | US...)
Affinity DataEC50:  290nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255776(2-(4-(4-n-Octylphenyl)piperazin-1-yl)acetic acid |...)
Affinity DataEC50:  1.63E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255777(3-(3-(4-n-Octylphenyl)ureido)propanoic acid | US97...)
Affinity DataEC50:  460nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255778(3-(3-(4-Octylphenyl)-2-oxoimidazolidin-1-yl)propan...)
Affinity DataEC50:  3.21E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255779(US9707205, 17)
Affinity DataEC50:  1.76E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255780(4-(4-(3-(3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl)p...)
Affinity DataEC50:  5.99E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255781(1-((4′-(((4-Fluorophenyl)(isopropyl)amino)me...)
Affinity DataEC50:  600nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255782(1-((4′-(3-(3-(Trifluoromethyl)phenyl)but-2-e...)
Affinity DataEC50:  200nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255783(1-(4-(3-(1-Admantnyl)-4-methoxybenzyloxy)benzyl)az...)
Affinity DataEC50:  60nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255784(1-(4-(2-(6,6-Dimethylbicyclo[3.1.1]heptan-2-yl)eth...)
Affinity DataEC50:  140nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255785(2-Amino-2-(5-(5-(3-chloro-4-propoxyphenyl)-1,2,4-o...)
Affinity DataEC50:  47nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255786( (E)-2-Amino-2-(5-(5-(4-methylstyryl)-1,2,4-oxadia...)
Affinity DataEC50:  1.82E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255787( 2-Amino-2-(5-(5-(4-bromo-3-chlorophenyl)-1,2,4-ox...)
Affinity DataEC50:  260nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255788(2-Amino-2-(5-(5-(3-chloro-4-(thiophen-3-yl)phenyl)...)
Affinity DataEC50:  3.46E+3nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM255789(2-Amino-2-(5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  57nMAssay Description:Selected Compounds of the Examples were evaluated at Millipore Corporation, USA, using S1P1 receptor; [35S]-GTPgamaS binding assay. A [35S]-GTPgamaS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM290032(US9572792, Compound 6 | N-(3-bromopyridin-4-yl)-7-...)
Affinity DataEC50:  19nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM290121(US9572792, Compound 5 | N-(2-bromophenyl)-7-methox...)
Affinity DataEC50:  26.4nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM290122(US9572792, Compound 62 | (4R)-4-amino-5-[(4-{[(7-m...)
Affinity DataEC50:  3.10nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM290123(US9572792, Compound 38 | N-[4-(aminosulfonyl)-2-br...)
Affinity DataEC50:  3.5nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM290124(US9572792, Compound 49 | N-{4-[(ethylsulfonyl)amin...)
Affinity DataEC50:  14.3nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM317450(US9617250, Example 57 of D1)
Affinity DataEC50:  0.300nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM317451(US9617250, Example 101 of D1)
Affinity DataEC50:  0.400nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM317452(US9617250, S-entiomer of Example 22 of D1)
Affinity DataEC50:  0.100nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM317453(US9617250, Example 1 Example 204 of D1 | BDBM50165...)
Affinity DataEC50:  0.200nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM317454(US9617250, Example 233 of D1)
Affinity DataEC50:  0.200nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM50080558(CHEMBL3126601 | US9617250, Example 1)
Affinity DataEC50:  2.10nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM50080575(CHEMBL3126602 | US9617250, Example 2)
Affinity DataEC50:  0.700nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Abbvie

US Patent
LigandPNGBDBM50080574(CHEMBL3126603 | US9617250, Example 3)
Affinity DataEC50:  0.300nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

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