Compile Data Set for Download or QSAR
Report error Found 1270 for UniProtKB: P28062
LigandPNGBDBM50518761(CHEMBL4573271)
Affinity DataEC50:  2.40E+4nMAssay Description:Stimulation of human 20S proteasome using 11 amino acid FRET peptide as substrate measured every 2 mins over 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50518762(CHEMBL4561568)
Affinity DataEC50:  3.50E+4nMAssay Description:Stimulation of human 20S proteasome using 11 amino acid FRET peptide as substrate measured every 2 mins over 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50054471(cid_6604822 | (5Z,8Z)-Icosa-5,8,11,14-tetraenoic a...)
Affinity DataEC50:  2.80E+4nMAssay Description:Stimulation of human 20S proteasome using 11 amino acid FRET peptide as substrate measured every 2 mins over 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  9.18E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50526811(Kzr-616)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50554392(CHEMBL4751044)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50554394(CHEMBL4784875)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50476098(Cinnabaramide G)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50554397(CHEMBL4741140)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50234982(CHEMBL4102324)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50604290(CHEMBL5175132)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50476095(CINNABARAMIDE A)
Affinity DataIC50: 1nMAssay Description:Inhibition of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50234984(CHEMBL3218837)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S immunoproteasome beta 5i subunit in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of PA28alpha by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50604328(CHEMBL5180795)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50554389(CHEMBL4796570)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50604287(CHEMBL5201806)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50099832(CHEMBL3319587)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
LigandPNGBDBM50550643(CHEMBL4749207)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50398608(MARIZOMIB)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 20S proteasome (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50099830(CHEMBL3319585)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
LigandPNGBDBM50531806(CHEMBL4460323)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50554385(CHEMBL4764897)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50554386(CHEMBL4758484)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50604327(CHEMBL5202276)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM388435(US10294246, Compound No. 132)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM388321(US10294246, Compound No. 18)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50601652(CHEMBL5191857)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50031442(Alpha-ketocarbonyl derivative | 1N-[4-amino(nitroi...)
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for inhibitory activity against 20S proteasome from human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 subunit chymotrypsin-like activity using fluorogenic peptide Ac-WLA-AMC as substrate in presence of P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50604289(CHEMBL5181060)
Affinity DataIC50: 2nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50099659(CHEMBL3319478)
Affinity DataIC50: 2nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
LigandPNGBDBM388309(US10294246, Compound No. 6)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50099831(CHEMBL3319586)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
LigandPNGBDBM388395(US10294246, Compound No. 92)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50554384(CHEMBL4784015)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM388323(US10294246, Compound No. 20)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM388311(US10294246, Compound No. 8)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50531814(CHEMBL4517600)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50554395(CHEMBL4763116)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50514365(CHEMBL4587036)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
LigandPNGBDBM50604330(CHEMBL5207139)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM388437(US10294246, Compound No. 134)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50604288(CHEMBL5205273)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50604324(CHEMBL5183361)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50329819((R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)b...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandPNGBDBM50099685(CHEMBL3319578)
Affinity DataIC50: 3nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 1270 total ) | Next | Last >>
Jump to: