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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303061(US9598447, Ref No. AA)
Affinity DataEC50:  184nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303062(US9598447, Ref No. BB)
Affinity DataEC50:  197nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303063(US9598447, Ref No. DD)
Affinity DataEC50:  174nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303064(US9598447, Ref No. FF)
Affinity DataEC50:  2.49nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303065(US9598447, Ref No. HH)
Affinity DataEC50:  19.3nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303066(US9598447, Ref No. KK)
Affinity DataEC50:  658nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303067(US9598447, Ref No. MM)
Affinity DataEC50:  10.8nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303068(US9598447, Ref No. OO)
Affinity DataEC50:  2.92nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303069(US9598447, Ref No. PP)
Affinity DataEC50:  2.32nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303070(US9598447, Ref No. QQ)
Affinity DataEC50:  8.90nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303071(US9598447, Ref No. TT)
Affinity DataEC50:  3.94nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303072(US9598447, Ref No. VV)
Affinity DataEC50:  15nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303073(US9598447, Ref No. WW)
Affinity DataEC50:  13.8nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM303074(US9598447, Ref No. XX)
Affinity DataEC50:  26.6nMAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473472(CHEMBL412537)
Affinity DataEC50:  0.251nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50106479(FGGFTGARKSARK | H-FGGFTGARKSARK-NH2 | NC(1-13)NH2 ...)
Affinity DataEC50:  0.324nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473473(CHEMBL406097)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50106477(FGGFTGARKSARKLADE | Phe-GGFTGARKSARKLAD-Glu | CHEM...)
Affinity DataEC50:  0.219nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473474(CHEMBL405648)
Affinity DataEC50:  0.269nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473475(CHEMBL428668)
Affinity DataEC50:  1nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473471(CHEMBL415583)
Affinity DataEC50:  63nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473478(CHEMBL409204)
Affinity DataEC50:  0.135nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473480(CHEMBL262224)
Affinity DataEC50:  11nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473477(CHEMBL427791)
Affinity DataEC50:  0.302nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473476(CHEMBL261997)
Affinity DataEC50:  0.158nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473483(CHEMBL410167)
Affinity DataEC50:  7.20nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473479(CHEMBL262928)
Affinity DataEC50:  257nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473482(CHEMBL265544)
Affinity DataEC50:  32nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50473481(CHEMBL265392)
Affinity DataEC50:  135nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  1nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50472747(CHEMBL414767)
Affinity DataEC50:  0.759nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475327(CHEMBL410653)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  0.115nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475329(CHEMBL263588)
Affinity DataEC50:  0.479nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475331(CHEMBL411649)
Affinity DataEC50:  4.90nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475327(CHEMBL410653)
Affinity DataEC50:  0.141nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475329(CHEMBL263588)
Affinity DataEC50:  0.813nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475330(CHEMBL442297)
Affinity DataEC50:  0.302nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475331(CHEMBL411649)
Affinity DataEC50:  0.407nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing human NOP receptor (CHOhNOP) More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475325(CHEMBL262544)
Affinity DataEC50:  0.933nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475333(CHEMBL264846)
Affinity DataEC50:  0.0661nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475325(CHEMBL262544)
Affinity DataEC50:  0.240nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475332(CHEMBL413944)
Affinity DataEC50:  5.90nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP) at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475333(CHEMBL264846)
Affinity DataEC50:  0.309nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475332(CHEMBL413944)
Affinity DataEC50:  55nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475328(CHEMBL414782)
Affinity DataEC50:  0.0759nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475328(CHEMBL414782)
Affinity DataEC50:  0.0676nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50472747(CHEMBL414767)
Affinity DataEC50:  5.20nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50475330(CHEMBL442297)
Affinity DataEC50:  0.209nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM50514547(CHEMBL4451073)
Affinity DataEC50:  249nMAssay Description:Agonist activity at human NOP expressed in CHO cell membrane incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
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