Compile Data Set for Download or QSAR
Report error Found 299 of affinity data for UniProtKB/TrEMBL: Q3TBT3
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataKd: <0.0100nMAssay Description:Binding affinity to wild type mouse STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataKd:  0.0200nMAssay Description:Binding affinity to wild type mouse STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM501204(US11021511, Compound 4)
Affinity DataIC50: 2nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50: 2.60nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataIC50: 7.70nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM501363(US11021511, Compound 6b)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM501364(US11021511, Compound 6c)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandPNGBDBM501361(US11021511, Compound 5)
Affinity DataIC50: 16nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM50584871(CHEMBL5080916)
Affinity DataIC50: 50nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  54nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  130nMAssay Description:Binding affinity to mouse STING by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50610502(CHEMBL166512)
Affinity DataKd:  130nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataEC50:  180nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50587698(CHEMBL5187053)
Affinity DataEC50:  186nMAssay Description:Agonist activity at mouse STING assessed as IFN-beta secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  186nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50584874(CHEMBL5081567)
Affinity DataIC50: 230nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50582523(CHEMBL5086820)
Affinity DataEC50:  280nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50584870(CHEMBL5082881)
Affinity DataIC50: 370nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50582522(CHEMBL5092444)
Affinity DataEC50:  500nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50584881(CHEMBL5082361)
Affinity DataIC50: 540nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50558671(CHEMBL4751982)
Affinity DataEC50:  600nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50582522(CHEMBL5092444)
Affinity DataEC50:  700nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50587691(CHEMBL5206214)
Affinity DataKd:  710nMAssay Description:Binding affinity to mouse STING (154 to 340 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  710nMAssay Description:Binding affinity to mouse STING assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50582523(CHEMBL5086820)
Affinity DataEC50:  760nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50617083(CHEMBL5416014)
Affinity DataIC50: 930nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50584871(CHEMBL5080916)
Affinity DataEC50:  940nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50617085(CHEMBL5424638)
Affinity DataIC50: 960nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523203(US11161864, Example 27D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523155(US11161864, Example 7C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523156(US11161864, Example 7D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523207(US11161864, Example 29B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523159(US11161864, Example 10)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523149(US11161864, Example 5A)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523199(US11161864, Example 21C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523151(US11161864, Example 6A)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523152(US11161864, Example 6B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523201(US11161864, Example 27B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523153(US11161864, Example 7A)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523202(US11161864, Example 27C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523154(US11161864, Example 7B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523215(US11161864, Example 34C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523172(US11161864, Example 19D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523218(US11161864, Example 36D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523173(US11161864, Example 17C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523160(US11161864, Example 18C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523210(US11161864, Example 22C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523164(US11161864, Example 15A)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523211(US11161864, Example 22D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523165(US11161864, Example 15C)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

Displayed 1 to 50 (of 299 total ) | Next | Last >>
Jump to: