Compile Data Set for Download or QSAR
Report error Found 359 of affinity data for UniProtKB/TrEMBL: Q3TBT3
LigandChemical structure of BindingDB Monomer ID 50506263BDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataKd: <0.0100nMAssay Description:Binding affinity to wild type mouse STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 573971BDBM573971(US11453697, Example 247)
Affinity DataKd:  0.0200nMAssay Description:Binding affinity to wild type mouse STING assessed as dissociation constant by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50506263BDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataIC50: 0.630nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 501204BDBM501204(US11021511, Compound 4)
Affinity DataIC50: 2nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50509050BDBM50509050(CHEMBL4438309)
Affinity DataIC50: 2.60nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 7.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50558665BDBM50558665(CHEMBL4776666)
Affinity DataIC50: 7.70nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 501363BDBM501363(US11021511, Compound 6b)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 501364BDBM501364(US11021511, Compound 6c)
Affinity DataIC50: 10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [138-378](Mouse)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 501361BDBM501361(US11021511, Compound 5)
Affinity DataIC50: 16nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50668728BDBM50668728(CHEMBL6190233)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50668746BDBM50668746(CHEMBL6189179)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50668747BDBM50668747(CHEMBL6190580)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50584871BDBM50584871(CHEMBL5080916)
Affinity DataIC50: 50nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50661010BDBM50661010(CHEMBL6163886)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50509050BDBM50509050(CHEMBL4438309)
Affinity DataEC50:  54nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50661002BDBM50661002(CHEMBL6151719)
Affinity DataIC50: 96nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50605474BDBM50605474(CHEMBL5189857)
Affinity DataIC50: 107nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 112nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50605474BDBM50605474(CHEMBL5189857)
Affinity DataIC50: 128nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50511078BDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  130nMAssay Description:Binding affinity to mouse STING by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50610502BDBM50610502(CHEMBL166512)
Affinity DataKd:  130nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50558665BDBM50558665(CHEMBL4776666)
Affinity DataEC50:  180nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587698BDBM50587698(CHEMBL5187053)
Affinity DataEC50:  186nMAssay Description:Agonist activity at mouse STING assessed as IFN-beta secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50509050BDBM50509050(CHEMBL4438309)
Affinity DataEC50:  186nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50665897BDBM50665897(CHEMBL6175377)
Affinity DataEC50:  200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 202nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50661008BDBM50661008(CHEMBL6147253)
Affinity DataIC50: 210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50661006BDBM50661006(CHEMBL6143097)
Affinity DataIC50: 229nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50584874BDBM50584874(CHEMBL5081567)
Affinity DataIC50: 230nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50605474BDBM50605474(CHEMBL5189857)
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50582523BDBM50582523(CHEMBL5086820)
Affinity DataEC50:  280nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50661009BDBM50661009(CHEMBL6149477)
Affinity DataIC50: 305nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50584870BDBM50584870(CHEMBL5082881)
Affinity DataIC50: 370nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50660981BDBM50660981(CHEMBL6148469)
Affinity DataIC50: 407nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50660982BDBM50660982(CHEMBL6170454)
Affinity DataIC50: 457nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50582522BDBM50582522(CHEMBL5092444)
Affinity DataEC50:  500nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50584881BDBM50584881(CHEMBL5082361)
Affinity DataIC50: 540nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50558671BDBM50558671(CHEMBL4751982)
Affinity DataEC50:  600nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50582522BDBM50582522(CHEMBL5092444)
Affinity DataEC50:  700nMAssay Description:Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587691BDBM50587691(CHEMBL5206214)
Affinity DataKd:  710nMAssay Description:Binding affinity to mouse STING (154 to 340 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50511078BDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  710nMAssay Description:Binding affinity to mouse STING assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50582523BDBM50582523(CHEMBL5086820)
Affinity DataEC50:  760nMAssay Description:Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50660990BDBM50660990(CHEMBL6146138)
Affinity DataIC50: 776nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50660991BDBM50660991(CHEMBL6151728)
Affinity DataIC50: 815nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50665897BDBM50665897(CHEMBL6175377)
Affinity DataEC50:  900nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50617083BDBM50617083(CHEMBL5416014)
Affinity DataIC50: 930nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50584871BDBM50584871(CHEMBL5080916)
Affinity DataEC50:  940nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50617085BDBM50617085(CHEMBL5424638)
Affinity DataIC50: 960nMAssay Description:Agonist activity at mouse 6His-tagged recombinant STING CTD (144 to 378 residues) expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
Displayed 1 to 50 (of 359 total ) | Next | Last >>
Jump to: