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Found 137 for UniProtKB: Q9Z2V5
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  0.625nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))
Affinity DataIC50:  3.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10(Mus musculus)
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50221738(CHEMBL1790595)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))
Affinity DataIC50:  7.5nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222728(CHEMBL394261 | cyclo(-L-Am7(S2Py)-A2in-L-Ala-D-Pro...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50540612(CHEMBL4636622)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222735(CHEMBL390991 | cyclo(-L-Am7(S2Py)-D-A1in-L-Ala-D-P...)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against histone deacetylase 6 prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)
Affinity DataIC50:  23nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222736(CHEMBL241555 | cyclo(-L-Am7(S2Py)-Aib-L-Ser(Bzl)-D...)
Affinity DataIC50:  24nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222733(CHEMBL393961 | cyclo(-L-Am7(S2Py)-Aib-L-Ser-D-Pro-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  28nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against histone deacetylase 6 prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50366966(CHEMBL1790596)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against histone deacetylase 6 prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)
Affinity DataIC50:  29nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))
Affinity DataIC50:  29nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222726(CHEMBL393260 | cyclo(-L-Am7(S2Py)-L-A1in-L-Ala-D-P...)
Affinity DataIC50:  33nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))
Affinity DataIC50:  34nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  36nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222729(CHEMBL391384 | cyclo(-L-Am7(S2Py)-Aib-L-Ph5-D-Pro-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  43nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50460520(CHEMBL4228293)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)
Affinity DataIC50:  45nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM218202(US9249087, 43)
Affinity DataIC50:  46nMAssay Description:Inhibition of HDAC6 in mouse N2A cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50460521(CHEMBL4228332)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50:  54nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50558325(CHEMBL4746359)
Affinity DataIC50:  55nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222730(CHEMBL393464 | cyclo(-L-Am7(S2Py)-L-2MePhe-L-Ala-D...)
Affinity DataIC50:  56nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  65nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)
Affinity DataIC50:  71nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222731(CHEMBL393261 | cyclo(-L-Am7(S2Py)-D-2MePhe-L-Ala-D...)
Affinity DataIC50:  71nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50:  78nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50460518(CHEMBL4228977)
Affinity DataIC50:  81nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  81nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19138(tert-butyl N-[(1S)-1-(adamantan-1-ylcarbamoyl)-6-s...)
Affinity DataIC50:  82nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048862(CHEMBL3310510)
Affinity DataIC50:  83nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10(Mus musculus)
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50366962(CHEMBL1790586)
Affinity DataIC50:  84nMAssay Description:Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50222734(CHEMBL428737 | cyclo(-L-Am7(S2Py)-Aib-L-Phg-D-Pro-...)
Affinity DataIC50:  86nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM19144((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50048858(CHEMBL3310506)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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