BDBM50025691 2-(2-Ethoxy-phenoxymethyl)-morpholine::2-(2-Ethoxy-phenoxymethyl)-morpholine (viloxazine)::2-(2-Ethoxy-phenoxymethyl)-morpholine(viloxazine)::CHEMBL306700::VILOXAZINE

SMILES CCOc1ccccc1OCC1CNCCO1

InChI Key InChIKey=YWPHCCPCQOJSGZ-UHFFFAOYSA-N

Data  6 KI  3 Kd

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50025691   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi:  155nMMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi:  170nMAssay Description:Inhibition of [3H]- NE reuptake into rat hippocampal synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of [3H]5-HT reuptake into rat frontal cortex synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of [3H]- DA reuptake into rat striatal synaptosomesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKd:  1.73E+4nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERTMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKd:  155nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50025691(2-(2-Ethoxy-phenoxymethyl)-morpholine | 2-(2-Ethox...)
Show SMILES CCOc1ccccc1OCC1CNCCO1
Show InChI InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3
Affinity DataKd:  155nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDATMore data for this Ligand-Target Pair