Affinity DataEC50: 780nMAssay Description:Antagonist activity at human EGFP-fused CCR3 expressed in mouse L1.2 cells assessed as inhibition of CCL11-induced chemotaxis measured after 1.5 hrs ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Antagonist activity at human EGFP-fused CCR3 expressed in mouse L1.2 cells assessed as inhibition of CCL11-induced chemotaxis measured after 1.5 hrs ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Antagonist activity at human EGFP-fused CCR3 expressed in mouse L1.2 cells assessed as inhibition of CCL11-induced chemotaxis measured after 1.5 hrs ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Antagonist activity at human EGFP-fused CCR3 expressed in mouse L1.2 cells assessed as inhibition of CCL11-induced chemotaxis measured after 1.5 hrs ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at CCR3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125Iodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Assay is described in WO 2010 115836.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125Iodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125lodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity at human CCR3 assessed as inhibition of CCL11-induced calcium influx by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125lodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Assay is described in WO 2010 115836.More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125Iodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125Iodine-eotaxi...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:The CCR3 receptor binding assay was performed in a Scintillation Proximity Assay (SPA) design with the radioligand recombinant human 125lodine-eotaxi...More data for this Ligand-Target Pair